Last reviewed · How we verify
CCNU — Competitive Intelligence Brief
phase 3
Nitrosourea alkylating agent
DNA (non-selective alkylating agent)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CCNU (CCNU) — Radiation Therapy Oncology Group. CCNU (lomustine) is a nitrosourea alkylating agent that cross-links DNA strands, preventing cell replication and inducing cancer cell death.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CCNU TARGET | CCNU | Radiation Therapy Oncology Group | phase 3 | Nitrosourea alkylating agent | DNA (non-selective alkylating agent) | |
| Carmustine BCNU | Carmustine BCNU | Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie | phase 3 | Nitrosourea alkylating agent | DNA (non-specific alkylating agent) | |
| Lomustine Chemotherapy | Lomustine Chemotherapy | AstraZeneca | phase 3 | Nitrosourea alkylating agent | DNA (non-selective alkylating agent) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nitrosourea alkylating agent class)
- AstraZeneca · 1 drug in this class
- Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie · 1 drug in this class
- Radiation Therapy Oncology Group · 1 drug in this class
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- CCNU CI watch — RSS
- CCNU CI watch — Atom
- CCNU CI watch — JSON
- CCNU alone — RSS
- Whole Nitrosourea alkylating agent class — RSS
Cite this brief
Drug Landscape (2026). CCNU — Competitive Intelligence Brief. https://druglandscape.com/ci/ccnu. Accessed 2026-05-13.
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