Who are Gliadel's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): L-Lysine, Carmustin, Pepaxto, Zepzelca, Yondelis, Treanda.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Gliadel — Competitive Intelligence Brief

Gliadel (CARMUSTINE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkylating Drug. Area: Oncology.

marketed Alkylating Drug Glutathione reductase, mitochondrial Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Gliadel (CARMUSTINE) — Avet Lifesciences. Gliadel works by attaching an alkyl group to the DNA of cancer cells, interfering with their ability to replicate and grow.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Gliadel TARGET	CARMUSTINE	Avet Lifesciences	marketed	Alkylating Drug	Glutathione reductase, mitochondrial	1977-01-01
L-Lysine	LYSINE	Advanced Accelerator Applications	marketed	lysine	Glutathione reductase, mitochondrial
Carmustin	Carmustin	University Hospital Freiburg	marketed		Glutathione reductase, mitochondrial
Pepaxto	MELPHALAN FLUFENAMIDE	Oncopeptides Ab	marketed	Alkylating Drug		2021-01-01
Zepzelca	LURBINECTEDIN	Jazz Pharmaceuticals	marketed	Alkylating Drug [EPC]		2020-01-01
Yondelis	TRABECTEDIN	Janssen Prods	marketed	Alkylating Drug [EPC]	Proto-oncogene tyrosine-protein kinase Src	2015-01-01
Treanda	BENDAMUSTINE	Baxter	marketed	Alkylating Drug	Histone deacetylase 6	2008-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2032-04-25 — Pepaxto · 10285946 · US
2032-04-25 — Pepaxto · 10322182 · US
2032-04-25 — Pepaxto · 10543274 · US
2032-04-25 — Pepaxto · 10869928 · US
2032-04-25 — Pepaxto · 11344622 · US

Sponsor landscape (Alkylating Drug class)

· 1 drug in this class
Apotex · 1 drug in this class
Avet Lifesciences · 1 drug in this class
Baxter · 1 drug in this class
Eisai · 1 drug in this class
Leadiant Biosci Inc · 1 drug in this class
Oncopeptides Ab · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Gliadel — Competitive Intelligence Brief. https://druglandscape.com/ci/carmustine. Accessed 2026-05-13.

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