Who are Carfilzomib Lenalidomide Dexamethasone's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Drug: Carfilzomib + Lenalidomide + Dexamethasone, VRD for first-cycle induction therapy, Bortezomib/Lenalidomide/ Low dose Dex.

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Last reviewed 2026-05-17 · How we verify

Carfilzomib Lenalidomide Dexamethasone — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Carfilzomib Lenalidomide Dexamethasone (Carfilzomib Lenalidomide Dexamethasone) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination. Area: Oncology.

phase 3 Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination 20S proteasome (carfilzomib); Cereblon/E3 ubiquitin ligase (lenalidomide); Glucocorticoid receptor (dexamethasone) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Carfilzomib Lenalidomide Dexamethasone (Carfilzomib Lenalidomide Dexamethasone) — European Myeloma Network B.V.. This combination therapy kills multiple myeloma cells by inhibiting the proteasome (carfilzomib), modulating cereblon-mediated protein degradation (lenalidomide), and suppressing inflammatory cytokines (dexamethasone).

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Carfilzomib Lenalidomide Dexamethasone TARGET	Carfilzomib Lenalidomide Dexamethasone	European Myeloma Network B.V.	phase 3	Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination	20S proteasome (carfilzomib); Cereblon/E3 ubiquitin ligase (lenalidomide); Glucocorticoid receptor (dexamethasone)
Drug: Carfilzomib + Lenalidomide + Dexamethasone	Drug: Carfilzomib + Lenalidomide + Dexamethasone	Amgen	marketed	Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination	20S proteasome (carfilzomib); cereblon/CRBN (lenalidomide); glucocorticoid receptor (dexamethasone)
VRD for first-cycle induction therapy	VRD for first-cycle induction therapy	The First Affiliated Hospital of Soochow University	marketed	Proteasome inhibitor + immunomodulatory agent + corticosteroid combination	26S proteasome (bortezomib); cereblon/CRBN (lenalidomide); glucocorticoid receptor (dexamethasone)
Bortezomib/Lenalidomide/ Low dose Dex	Bortezomib/Lenalidomide/ Low dose Dex	King Faisal Specialist Hospital & Research Center	phase 3	Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination	Proteasome (bortezomib); Cereblon (lenalidomide); Glucocorticoid receptor (dexamethasone)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination class)

Amgen · 1 drug in this class
European Myeloma Network B.V. · 1 drug in this class
King Faisal Specialist Hospital & Research Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Carfilzomib Lenalidomide Dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/carfilzomib-lenalidomide-dexamethasone. Accessed 2026-05-17.

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