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Tegretol — Competitive Intelligence Brief
marketed
Mood Stabilizer [EPC]
Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Tegretol (carbamazepine) — Novartis AG (originally Geigy). Carbamazepine reduces polysynaptic responses and blocks post-tetanic potentiation, potentially alleviating seizures and pain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tegretol TARGET | carbamazepine | Novartis AG (originally Geigy) | marketed | Mood Stabilizer [EPC] | Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4 | 1968-03-11 |
| Carbamazepin | Carbamazepin | Enanta Pharmaceuticals, Inc | marketed | Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4 | ||
| Lithobid | lithium carbonate | Generic (multiple manufacturers) | marketed | Mood stabilizer | Inositol-1(or 4)-monophosphatase 1, Glycogen synthase kinase-3 | 1970-04-06 |
| CARBAMAZEPINE | CARBAMAZEPINE | marketed | Mood Stabilizer [EPC] | 1968-01-01 | ||
| lamotrigine (generic Teva) | lamotrigine (generic Teva) | University of Maryland, Baltimore | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release inhibition | |
| Lithium / Fluoxetine | Lithium / Fluoxetine | University of Pennsylvania | marketed | SSRI + mood stabilizer combination | Serotonin transporter (SERT); inositol monophosphatase | |
| lamotrigine (brand Lamictal) | lamotrigine (brand Lamictal) | University of Maryland, Baltimore | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release inhibition |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Tegretol · 9770407 · Formulation · US
- — Tegretol · 9629797 · Method of Use · US
- — Tegretol · 9750822 · Formulation · US
- — Tegretol · 7635773 · Formulation · US
- — Tegretol · 8410077 · Formulation · US
- — Tegretol · 9493582 · Formulation · US
- — Tegretol · 11529357 · Formulation · US
Sponsor landscape (Mood Stabilizer [EPC] class)
- · 1 drug in this class
- Novartis AG (originally Geigy) · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Tegretol — Competitive Intelligence Brief. https://druglandscape.com/ci/carbamazepine. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing