Who are Capsaicin Topical Cream's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Capsaicine low dose 0.04 %, Qutenza Patch, Capsaicin 8%, Topical capsaicin, NGX-4010, Intranasal capsaicin.

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Last reviewed 2026-05-16 · How we verify

Capsaicin Topical Cream — Competitive Intelligence Brief

Capsaicin Topical Cream (Capsaicin Topical Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical analgesic; TRPV1 agonist. Area: Pain Management.

marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1) Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

Capsaicin Topical Cream (Capsaicin Topical Cream) — Women and Infants Hospital of Rhode Island. Capsaicin activates TRPV1 pain receptors on nerve endings, causing initial stimulation followed by desensitization and depletion of substance P, reducing pain signal transmission.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Capsaicin Topical Cream TARGET	Capsaicin Topical Cream	Women and Infants Hospital of Rhode Island	marketed	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
Capsaicine low dose 0.04 %	Capsaicine low dose 0.04 %	University Hospital, Clermont-Ferrand	marketed	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
Qutenza Patch	Qutenza Patch	M.D. Anderson Cancer Center	marketed	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
Capsaicin 8%	Capsaicin 8%	Averitas Pharma, Inc.	marketed	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
Topical capsaicin	Topical capsaicin	The University of Texas Health Science Center, Houston	marketed	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
NGX-4010	NGX-4010	NeurogesX	phase 3	Topical analgesic; TRPV1 agonist	TRPV1 (transient receptor potential vanilloid 1)
Intranasal capsaicin	Intranasal capsaicin	The University of Texas Health Science Center, Houston	phase 3	TRPV1 agonist / Topical analgesic	TRPV1 (Transient Receptor Potential Vanilloid 1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical analgesic; TRPV1 agonist class)

Averitas Pharma, Inc. · 1 drug in this class
M.D. Anderson Cancer Center · 1 drug in this class
NeurogesX · 1 drug in this class
The University of Texas Health Science Center, Houston · 1 drug in this class
University Hospital, Clermont-Ferrand · 1 drug in this class
Women and Infants Hospital of Rhode Island · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Capsaicin Topical Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/capsaicin-topical-cream. Accessed 2026-05-16.

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