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Capsaicin 0.1% Cream — Competitive Intelligence Brief
phase 2
Topical analgesic
TRPV1
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Capsaicin 0.1% Cream (Capsaicin 0.1% Cream) — Henry Ford Health System. Activates TRPV1 receptors to reduce pain
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Capsaicin 0.1% Cream TARGET | Capsaicin 0.1% Cream | Henry Ford Health System | phase 2 | Topical analgesic | TRPV1 | |
| Cannabidiol oral oil | Cannabidiol oral oil | Hôpital le Vinatier | marketed | Cannabinoid | Multiple (5-HT1A, TRPV1, CB1, CB2, glycine receptors) | |
| dl-Methylphenidate plus Cannabidiol | dl-Methylphenidate plus Cannabidiol | University of Florida | marketed | Combination therapy: sympathomimetic amine plus phytocannabinoid | Dopamine transporter, norepinephrine transporter (methylphenidate); CB1/CB2 receptors, 5-HT1A, TRPV1 (cannabidiol) | |
| MediCabilis CBD Oil | MediCabilis CBD Oil | Gold Coast Hospital and Health Service | marketed | Cannabinoid | CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multiple targets) | |
| Acetaminophen IV/PO | Acetaminophen IV/PO | The University of Texas Health Science Center, Houston | marketed | Analgesic and antipyretic | Cyclooxygenase (COX) enzymes; possibly TRPV1 and other pain pathways | |
| CBD | CBD | Stero Biotechs Ltd. | marketed | Cannabinoid | 5-HT1A, TRPV1, GPR55, CB1 (allosteric), CB2 (allosteric) | |
| Qutenza Patch | Qutenza Patch | M.D. Anderson Cancer Center | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topical analgesic class)
- Bayer · 1 drug in this class
- EpiCept Corporation · 1 drug in this class
- Express Specialty Pharmacy · 1 drug in this class
- Georg Kägi, MD · 1 drug in this class
- Grünenthal GmbH · 1 drug in this class
- Henry Ford Health System · 1 drug in this class
- Johnson & Johnson Consumer and Personal Products Worldwide · 1 drug in this class
- NeurogesX · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Capsaicin 0.1% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/capsaicin-0-1-cream. Accessed 2026-05-16.
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