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Capsaicin 0.1% Cream — Competitive Intelligence Brief

Capsaicin 0.1% Cream (Capsaicin 0.1% Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical analgesic. Area: Dermatology.

phase 2 Topical analgesic TRPV1 Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Capsaicin 0.1% Cream (Capsaicin 0.1% Cream) — Henry Ford Health System. Activates TRPV1 receptors to reduce pain

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Capsaicin 0.1% Cream TARGET Capsaicin 0.1% Cream Henry Ford Health System phase 2 Topical analgesic TRPV1
Cannabidiol oral oil Cannabidiol oral oil Hôpital le Vinatier marketed Cannabinoid Multiple (5-HT1A, TRPV1, CB1, CB2, glycine receptors)
dl-Methylphenidate plus Cannabidiol dl-Methylphenidate plus Cannabidiol University of Florida marketed Combination therapy: sympathomimetic amine plus phytocannabinoid Dopamine transporter, norepinephrine transporter (methylphenidate); CB1/CB2 receptors, 5-HT1A, TRPV1 (cannabidiol)
MediCabilis CBD Oil MediCabilis CBD Oil Gold Coast Hospital and Health Service marketed Cannabinoid CB1 receptor, CB2 receptor, 5-HT1A receptor, TRPV1 receptor (multiple targets)
Acetaminophen IV/PO Acetaminophen IV/PO The University of Texas Health Science Center, Houston marketed Analgesic and antipyretic Cyclooxygenase (COX) enzymes; possibly TRPV1 and other pain pathways
CBD CBD Stero Biotechs Ltd. marketed Cannabinoid 5-HT1A, TRPV1, GPR55, CB1 (allosteric), CB2 (allosteric)
Qutenza Patch Qutenza Patch M.D. Anderson Cancer Center marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical analgesic class)

  1. Bayer · 1 drug in this class
  2. EpiCept Corporation · 1 drug in this class
  3. Express Specialty Pharmacy · 1 drug in this class
  4. Georg Kägi, MD · 1 drug in this class
  5. Grünenthal GmbH · 1 drug in this class
  6. Henry Ford Health System · 1 drug in this class
  7. Johnson & Johnson Consumer and Personal Products Worldwide · 1 drug in this class
  8. NeurogesX · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Capsaicin 0.1% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/capsaicin-0-1-cream. Accessed 2026-05-16.

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