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CAPOX 3 month — Competitive Intelligence Brief

CAPOX 3 month (CAPOX 3 month) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite. Area: Oncology.

phase 2 Antimetabolite Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

CAPOX 3 month (CAPOX 3 month) — NRG Oncology. Capecitabine is a thymidylate synthase inhibitor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CAPOX 3 month TARGET CAPOX 3 month NRG Oncology phase 2 Antimetabolite Thymidylate synthase
Xeloda capecitabine Cheplapharm marketed Nucleoside Metabolic Inhibitor [EPC] Thymidylate synthase 1998-01-01
Fudr FLOXURIDINE marketed Antimetabolite [EPC] Thymidylate synthase 1970-01-01
Folic Acid FOLIC ACID Pfizer marketed Vitamin C [EPC] Thymidylate synthase 1946-01-01
Anlotinib plus Pemetrexed Anlotinib plus Pemetrexed Henan Provincial People's Hospital marketed Multi-target tyrosine kinase inhibitor plus antifolate antimetabolite VEGFR, FGFR, RET, c-Kit (anlotinib); thymidylate synthase, DHFR, GARFT (pemetrexed)
5-fluoro-uracil 5-fluoro-uracil UNICANCER marketed Antimetabolite Thymidylate synthase; RNA and DNA incorporation
oxaliplatin plus capecitabine oxaliplatin plus capecitabine LiNing marketed Platinum-based chemotherapy combination DNA (oxaliplatin); thymidylate synthase (capecitabine/5-FU)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite class)

  1. Grupo Espanol Multidisciplinario del Cancer Digestivo · 2 drugs in this class
  2. NRG Oncology · 2 drugs in this class
  3. Bristol-Myers Squibb · 1 drug in this class
  4. EMD Serono Research & Development Institute, Inc. · 1 drug in this class
  5. GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
  6. Hoffmann-La Roche · 1 drug in this class
  7. Centre Oscar Lambret · 1 drug in this class
  8. Iwate Medical University · 1 drug in this class
  9. Janssen Research & Development, LLC · 1 drug in this class
  10. Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CAPOX 3 month — Competitive Intelligence Brief. https://druglandscape.com/ci/capox-3-month. Accessed 2026-05-13.

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