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CAPOX 3 month — Competitive Intelligence Brief
phase 2
Antimetabolite
Thymidylate synthase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CAPOX 3 month (CAPOX 3 month) — NRG Oncology. Capecitabine is a thymidylate synthase inhibitor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CAPOX 3 month TARGET | CAPOX 3 month | NRG Oncology | phase 2 | Antimetabolite | Thymidylate synthase | |
| Xeloda | capecitabine | Cheplapharm | marketed | Nucleoside Metabolic Inhibitor [EPC] | Thymidylate synthase | 1998-01-01 |
| Fudr | FLOXURIDINE | marketed | Antimetabolite [EPC] | Thymidylate synthase | 1970-01-01 | |
| Folic Acid | FOLIC ACID | Pfizer | marketed | Vitamin C [EPC] | Thymidylate synthase | 1946-01-01 |
| Anlotinib plus Pemetrexed | Anlotinib plus Pemetrexed | Henan Provincial People's Hospital | marketed | Multi-target tyrosine kinase inhibitor plus antifolate antimetabolite | VEGFR, FGFR, RET, c-Kit (anlotinib); thymidylate synthase, DHFR, GARFT (pemetrexed) | |
| 5-fluoro-uracil | 5-fluoro-uracil | UNICANCER | marketed | Antimetabolite | Thymidylate synthase; RNA and DNA incorporation | |
| oxaliplatin plus capecitabine | oxaliplatin plus capecitabine | LiNing | marketed | Platinum-based chemotherapy combination | DNA (oxaliplatin); thymidylate synthase (capecitabine/5-FU) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antimetabolite class)
- Grupo Espanol Multidisciplinario del Cancer Digestivo · 2 drugs in this class
- NRG Oncology · 2 drugs in this class
- Bristol-Myers Squibb · 1 drug in this class
- EMD Serono Research & Development Institute, Inc. · 1 drug in this class
- GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
- Centre Oscar Lambret · 1 drug in this class
- Iwate Medical University · 1 drug in this class
- Janssen Research & Development, LLC · 1 drug in this class
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CAPOX 3 month — Competitive Intelligence Brief. https://druglandscape.com/ci/capox-3-month. Accessed 2026-05-13.
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