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Capecitabine Oral Product — Competitive Intelligence Brief
phase 3
Antimetabolite; Fluoropyrimidine
Thymidylate synthase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Capecitabine Oral Product (Capecitabine Oral Product) — Abramson Cancer Center at Penn Medicine. Capecitabine is a prodrug that is converted to fluorouracil in the body, which inhibits thymidylate synthase and disrupts DNA synthesis to kill rapidly dividing cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Capecitabine Oral Product TARGET | Capecitabine Oral Product | Abramson Cancer Center at Penn Medicine | phase 3 | Antimetabolite; Fluoropyrimidine | Thymidylate synthase | |
| Xeloda | capecitabine | Cheplapharm | marketed | Nucleoside Metabolic Inhibitor [EPC] | Thymidylate synthase | 1998-01-01 |
| Fudr | FLOXURIDINE | marketed | Antimetabolite [EPC] | Thymidylate synthase | 1970-01-01 | |
| Folic Acid | FOLIC ACID | Pfizer | marketed | Vitamin C [EPC] | Thymidylate synthase | 1946-01-01 |
| Folferi and celecoxib | Folferi and celecoxib | Sherief Abd-Elsalam | marketed | Chemotherapy combination with COX-2 inhibitor | Topoisomerase I (irinotecan), thymidylate synthase (fluorouracil), COX-2 | |
| Irinotecan, 5FU, leucovorin | Irinotecan, 5FU, leucovorin | Asan Medical Center | marketed | Chemotherapy combination (topoisomerase I inhibitor + antimetabolite) | Topoisomerase I; thymidylate synthase | |
| Unitrim | BRODIMOPRIM | marketed | brodimoprim | Bifunctional dihydrofolate reductase-thymidylate synthase, Dihydrofolate reductase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antimetabolite; Fluoropyrimidine class)
- Abramson Cancer Center at Penn Medicine · 1 drug in this class
- Qilu Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Capecitabine Oral Product — Competitive Intelligence Brief. https://druglandscape.com/ci/capecitabine-oral-product. Accessed 2026-05-18.
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