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Capecitabine combined with Pyrotinib — Competitive Intelligence Brief
phase 3
Combination chemotherapy and tyrosine kinase inhibitor
Thymidylate synthase (capecitabine); HER1/EGFR, HER2, HER4 (pyrotinib)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Capecitabine combined with Pyrotinib (Capecitabine combined with Pyrotinib) — Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. Capecitabine is a prodrug that converts to 5-fluorouracil to inhibit thymidylate synthase, while pyrotinib is a pan-HER tyrosine kinase inhibitor that blocks HER1, HER2, and HER4 signaling.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Capecitabine combined with Pyrotinib TARGET | Capecitabine combined with Pyrotinib | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | phase 3 | Combination chemotherapy and tyrosine kinase inhibitor | Thymidylate synthase (capecitabine); HER1/EGFR, HER2, HER4 (pyrotinib) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination chemotherapy and tyrosine kinase inhibitor class)
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Capecitabine combined with Pyrotinib — Competitive Intelligence Brief. https://druglandscape.com/ci/capecitabine-combined-with-pyrotinib. Accessed 2026-05-18.
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