Who are Cadonilimab (AK104)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Nivolumab + Relatlimab, BAT2206, Durvalumab +Tremelimumab, MEDI4736 + Tremelimumab, SHR-A1811 for Injection, APVO101.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Cadonilimab (AK104) — Competitive Intelligence Brief

Cadonilimab (AK104) (Cadonilimab (AK104)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific monoclonal antibody; dual checkpoint inhibitor. Area: Oncology.

phase 3 Bispecific monoclonal antibody; dual checkpoint inhibitor PD-L1 and TIM-3 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Cadonilimab (AK104) (Cadonilimab (AK104)) — Guangxi Medical University. Cadonilimab is a bispecific antibody that simultaneously blocks PD-L1 and TIM-3 pathways to enhance anti-tumor immune responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Cadonilimab (AK104) TARGET	Cadonilimab (AK104)	Guangxi Medical University	phase 3	Bispecific monoclonal antibody; dual checkpoint inhibitor	PD-L1 and TIM-3
Nivolumab + Relatlimab	Nivolumab + Relatlimab	H. Lee Moffitt Cancer Center and Research Institute	marketed	Dual checkpoint inhibitor (PD-1 and LAG-3 inhibitor combination)	PD-1 and LAG-3
BAT2206	BAT2206	Bio-Thera Solutions	phase 3	Bispecific antibody; dual checkpoint inhibitor	Likely PD-1 and LAG-3 (or similar dual checkpoint targets)
Durvalumab +Tremelimumab	Durvalumab +Tremelimumab	AstraZeneca	phase 3	Dual checkpoint inhibitor combination (PD-L1 inhibitor + CTLA-4 inhibitor)	PD-L1 and CTLA-4
MEDI4736 + Tremelimumab	MEDI4736 + Tremelimumab	AstraZeneca	phase 3	Dual checkpoint inhibitor (PD-L1 inhibitor + CTLA-4 inhibitor)	PD-L1 and CTLA-4
SHR-A1811 for Injection	SHR-A1811 for Injection	Suzhou Suncadia Biopharmaceuticals Co., Ltd.	phase 3	Bispecific monoclonal antibody; dual checkpoint inhibitor
APVO101	APVO101	Medexus Pharma, Inc.	phase 3	Dual checkpoint inhibitor	PD-1 and CTLA-4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific monoclonal antibody; dual checkpoint inhibitor class)

Guangxi Medical University · 1 drug in this class
Suzhou Suncadia Biopharmaceuticals Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cadonilimab (AK104) — Competitive Intelligence Brief. https://druglandscape.com/ci/cadonilimab-ak104. Accessed 2026-05-16.

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