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Cabazitaxel (XRP6258) — Competitive Intelligence Brief
marketed
Taxane; microtubule stabilizer
β-tubulin (microtubule)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Cabazitaxel (XRP6258) (Cabazitaxel (XRP6258)) — Sanofi. Cabazitaxel is a microtubule-stabilizing taxane that binds to β-tubulin and prevents microtubule depolymerization, leading to cell cycle arrest and apoptosis in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Cabazitaxel (XRP6258) TARGET | Cabazitaxel (XRP6258) | Sanofi | marketed | Taxane; microtubule stabilizer | β-tubulin (microtubule) | |
| Paclitaxel, Carboplatin | Paclitaxel, Carboplatin | Queensland Centre for Gynaecological Cancer | marketed | Chemotherapy combination (taxane + platinum agent) | Microtubules (paclitaxel); DNA (carboplatin) | |
| Paclitaxel (albumin-bound) | Paclitaxel (albumin-bound) | Dai, Guanghai | marketed | Taxane; microtubule stabilizer | β-tubulin (microtubule) | |
| Docetaxel (DOC) | Docetaxel (DOC) | Sun Yat-sen University | marketed | Taxane; microtubule stabilizer | β-tubulin | |
| Docetaxel or albumin paclitaxel | Docetaxel or albumin paclitaxel | Shandong Cancer Hospital and Institute | marketed | Taxane; microtubule-stabilizing chemotherapy agent | β-tubulin (microtubule) | |
| nab-paclitaxel,Cisplatin | nab-paclitaxel,Cisplatin | Yang Jianjun, PhD | marketed | Chemotherapy combination (taxane + platinum agent) | Microtubules (paclitaxel); DNA (cisplatin) | |
| Docetaxel (D) | Docetaxel (D) | BeyondSpring Pharmaceuticals Inc. | marketed | Taxane; microtubule stabilizer | β-tubulin |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Taxane; microtubule stabilizer class)
- Sanofi · 2 drugs in this class
- Aravive, Inc. · 1 drug in this class
- Athenex, Inc. · 1 drug in this class
- Barts & The London NHS Trust · 1 drug in this class
- BeyondSpring Pharmaceuticals Inc. · 1 drug in this class
- Bio-Thera Solutions · 1 drug in this class
- Dai, Guanghai · 1 drug in this class
- Fujian Medical University · 1 drug in this class
- Guangzhou Double Bioproducts Co., Ltd · 1 drug in this class
- H. Lee Moffitt Cancer Center and Research Institute · 1 drug in this class
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- Cabazitaxel (XRP6258) CI watch — RSS
- Cabazitaxel (XRP6258) CI watch — Atom
- Cabazitaxel (XRP6258) CI watch — JSON
- Cabazitaxel (XRP6258) alone — RSS
- Whole Taxane; microtubule stabilizer class — RSS
Cite this brief
Drug Landscape (2026). Cabazitaxel (XRP6258) — Competitive Intelligence Brief. https://druglandscape.com/ci/cabazitaxel-xrp6258. Accessed 2026-05-16.
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