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Butriptylene — Competitive Intelligence Brief
phase 2
butriptyline
Sodium-dependent serotonin transporter
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Butriptylene (BUTRIPTYLINE). Butriptyline works by blocking the reuptake of serotonin, a neurotransmitter involved in mood regulation, allowing more serotonin to be available in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Butriptylene TARGET | BUTRIPTYLINE | phase 2 | butriptyline | Sodium-dependent serotonin transporter | ||
| Fetzima | LEVOMILNACIPRAN | AbbVie | marketed | Serotonin and Norepinephrine Reuptake Inhibitor | Sodium-dependent serotonin transporter | 2013-01-01 |
| Pristiq | desvenlafaxine | Alembic Pharms Ltd | marketed | Serotonin and Norepinephrine Reuptake Inhibitor | Sodium-dependent serotonin transporter | 2008-01-01 |
| Celexa | CITALOPRAM | AbbVie | marketed | Serotonin Reuptake Inhibitor | Sodium-dependent serotonin transporter | 1998-01-01 |
| Plavix | clopidogrel | Generic (originally Sanofi/BMS) | marketed | Thienopyridine antiplatelet agent | Cytochrome P450 2B6, P2Y purinoceptor 12, Sodium-dependent serotonin transporter | 1997-11-17 |
| Racemic Sibutramine | SIBUTRAMINE | marketed | Norepinephrine, Serotonin, and Dopamine Reuptake Inhibitor Anorectic | Sodium-dependent serotonin transporter | 1997-01-01 | |
| Luvox | FLUVOXAMINE | marketed | Serotonin Reuptake Inhibitor | Sodium-dependent serotonin transporter | 1994-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
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Sponsor landscape (butriptyline class)
- · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Butriptylene — Competitive Intelligence Brief. https://druglandscape.com/ci/butriptyline. Accessed 2026-06-10.
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