Who are Stadol Preservative Free's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Korsuva, Remitch, Halflytely, Revex, Codeine, MS Contin.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

Stadol Preservative Free — Competitive Intelligence Brief

Stadol Preservative Free (BUTORPHANOL) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Opioid Agonist/Antagonist. Area: Neuroscience.

marketed Opioid Agonist/Antagonist Kappa-type opioid receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Stadol Preservative Free (BUTORPHANOL).

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Stadol Preservative Free TARGET	BUTORPHANOL		marketed	Opioid Agonist/Antagonist	Kappa-type opioid receptor	1978-01-01
Korsuva	DIFELIKEFALIN	Vifor Intl	marketed	Kappa Opioid Receptor Agonist	Kappa-type opioid receptor	2021-01-01
Remitch	NALFURAFINE		marketed	nalfurafine	Kappa-type opioid receptor	2009-01-01
Halflytely	BISACODYL	Braintree	marketed	Stimulant Laxative [EPC]	Kappa-type opioid receptor	2004-01-01
Revex	NALMEFENE	Hikma	marketed	Opioid Antagonist	Kappa-type opioid receptor	1995-01-01
Codeine	codeine phosphate	Generic (multiple manufacturers)	marketed	Opioid analgesic, Antitussive	Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor	1950-01-01
MS Contin	morphine sulfate	Generic (multiple manufacturers)	marketed	Opioid analgesic	Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor	1941-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2028-08-12 — MS Contin · 7955619 · Formulation · US
2028-08-12 — MS Contin · 10314788 · Formulation · US
2033-07-01 — MS Contin · 9044402 · Formulation · US
2033-07-01 — MS Contin · 9549899 · Formulation · US
2034-03-12 — MS Contin · 9248229 · Formulation · US
2034-03-12 — MS Contin · 9192608 · Method of Use · US
2034-03-12 — MS Contin · 9072781 · Formulation · US

Sponsor landscape (Opioid Agonist/Antagonist class)

· 1 drug in this class

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Cite this brief

Drug Landscape (2026). Stadol Preservative Free — Competitive Intelligence Brief. https://druglandscape.com/ci/butorphanol. Accessed 2026-05-15.

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