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Buspirone and Grapefruit Juice — Competitive Intelligence Brief
marketed
Serotonin 5-HT1A receptor partial agonist (buspirone component)
5-HT1A receptor (buspirone); CYP3A4 enzyme (grapefruit juice inhibition)
Psychiatry / Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Buspirone and Grapefruit Juice (Buspirone and Grapefruit Juice) — North Dakota State University. Buspirone acts as a serotonin 5-HT1A receptor partial agonist, while grapefruit juice inhibits CYP3A4 metabolism, increasing buspirone bioavailability and plasma concentrations.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Buspirone and Grapefruit Juice TARGET | Buspirone and Grapefruit Juice | North Dakota State University | marketed | Serotonin 5-HT1A receptor partial agonist (buspirone component) | 5-HT1A receptor (buspirone); CYP3A4 enzyme (grapefruit juice inhibition) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Serotonin 5-HT1A receptor partial agonist (buspirone component) class)
- North Dakota State University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Buspirone and Grapefruit Juice — Competitive Intelligence Brief. https://druglandscape.com/ci/buspirone-and-grapefruit-juice. Accessed 2026-05-16.
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