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Bupivacaine + nalbuphine — Competitive Intelligence Brief
marketed
Local anesthetic + mixed opioid agonist-antagonist
Voltage-gated sodium channels (bupivacaine); kappa and mu opioid receptors (nalbuphine)
Pain management, Anesthesia
Small molecule
Live · refreshed every 30 min
Target snapshot
Bupivacaine + nalbuphine (Bupivacaine + nalbuphine) — Alzahraa Ahmed Abbas. Bupivacaine provides local anesthesia by blocking sodium channels in nerve fibers, while nalbuphine provides opioid analgesia by acting as a mixed kappa agonist and mu antagonist.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Bupivacaine + nalbuphine TARGET | Bupivacaine + nalbuphine | Alzahraa Ahmed Abbas | marketed | Local anesthetic + mixed opioid agonist-antagonist | Voltage-gated sodium channels (bupivacaine); kappa and mu opioid receptors (nalbuphine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Local anesthetic + mixed opioid agonist-antagonist class)
- Alzahraa Ahmed Abbas · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Bupivacaine + nalbuphine — Competitive Intelligence Brief. https://druglandscape.com/ci/bupivacaine-nalbuphine. Accessed 2026-05-17.
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