Who are Brinzolamide/brimonidine ophthalmic suspension's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Simbrinza 0.2%-1% Ophthalmic Suspension, Brinzolamide/Brimonidine FC.

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Last reviewed 2026-05-18 · How we verify

Brinzolamide/brimonidine ophthalmic suspension — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Brinzolamide/brimonidine ophthalmic suspension (Brinzolamide/brimonidine ophthalmic suspension) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination. Area: Ophthalmology.

phase 3 Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination Carbonic anhydrase II; Alpha-2 adrenergic receptor Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Brinzolamide/brimonidine ophthalmic suspension (Brinzolamide/brimonidine ophthalmic suspension) — Padagis LLC. Brinzolamide reduces aqueous humor production via carbonic anhydrase inhibition, while brimonidine decreases aqueous humor production and increases uveoscleral outflow via alpha-2 adrenergic receptor agonism, together lowering intraocular pressure.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Brinzolamide/brimonidine ophthalmic suspension TARGET	Brinzolamide/brimonidine ophthalmic suspension	Padagis LLC	phase 3	Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination	Carbonic anhydrase II; Alpha-2 adrenergic receptor
Simbrinza 0.2%-1% Ophthalmic Suspension	Simbrinza 0.2%-1% Ophthalmic Suspension	Prairie Eye Center	marketed	Fixed-dose combination of carbonic anhydrase inhibitor and alpha-2 adrenergic agonist	Carbonic anhydrase II; alpha-2 adrenergic receptor
Brinzolamide/Brimonidine FC	Brinzolamide/Brimonidine FC	University Hospital of Patras	marketed	Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination	Carbonic anhydrase II; Alpha-2 adrenergic receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination class)

Padagis LLC · 1 drug in this class
University Hospital of Patras · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Brinzolamide/brimonidine ophthalmic suspension — Competitive Intelligence Brief. https://druglandscape.com/ci/brinzolamide-brimonidine-ophthalmic-suspension. Accessed 2026-05-18.

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