Who are Brexpiprazole (OPC-34712)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): OPC-34712FUM/ Brexpiprazole fumarate, Adjunct brexpiprazole.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Brexpiprazole (OPC-34712) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Brexpiprazole (OPC-34712) (Brexpiprazole (OPC-34712)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Atypical antipsychotic; serotonin-dopamine activity modulator (SDAM). Area: Psychiatry/Neurology.

phase 3 Atypical antipsychotic; serotonin-dopamine activity modulator (SDAM) Dopamine D2 receptor (partial agonist); serotonin 5-HT1A receptor (partial agonist); serotonin 5-HT2A receptor (antagonist) Psychiatry/Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Brexpiprazole (OPC-34712) (Brexpiprazole (OPC-34712)) — Otsuka Pharmaceutical Development & Commercialization, Inc.. Brexpiprazole is a serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors while antagonizing serotonin 5-HT2A receptors.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Brexpiprazole (OPC-34712) TARGET	Brexpiprazole (OPC-34712)	Otsuka Pharmaceutical Development & Commercialization, Inc.	phase 3	Atypical antipsychotic; serotonin-dopamine activity modulator (SDAM)	Dopamine D2 receptor (partial agonist); serotonin 5-HT1A receptor (partial agonist); serotonin 5-HT2A receptor (antagonist)
OPC-34712FUM/ Brexpiprazole fumarate	OPC-34712FUM/ Brexpiprazole fumarate	Otsuka Pharmaceutical Co., Ltd.	phase 3	Serotonin-dopamine activity modulator (SDAM); atypical antipsychotic	Dopamine D2 receptor (partial agonist), serotonin 5-HT1A receptor (partial agonist), serotonin 5-HT2A receptor (antagonist)
Adjunct brexpiprazole	Adjunct brexpiprazole	H. Lundbeck A/S	phase 3	Serotonin-dopamine activity modulator (SDAM)	Dopamine D2 receptor, Serotonin 5-HT1A receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Atypical antipsychotic; serotonin-dopamine activity modulator (SDAM) class)

Otsuka Pharmaceutical Development & Commercialization, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Brexpiprazole (OPC-34712) — Competitive Intelligence Brief. https://druglandscape.com/ci/brexpiprazole-opc-34712. Accessed 2026-05-16.

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