BPX-01 1% Minocycline Topical Gel — Competitive Intelligence Brief

BPX-01 1% Minocycline Topical Gel (BPX-01 1% Minocycline Topical Gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: tetracycline antibiotic. Area: Infectious Disease.

phase 2 tetracycline antibiotic 30S ribosomal subunit Infectious Disease Small molecule

Target snapshot

BPX-01 1% Minocycline Topical Gel (BPX-01 1% Minocycline Topical Gel) — BioPharmX, Inc.. Minocycline is a tetracycline antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
BPX-01 1% Minocycline Topical Gel TARGET	BPX-01 1% Minocycline Topical Gel	BioPharmX, Inc.	phase 2	tetracycline antibiotic	30S ribosomal subunit
Tygacil	TIGECYCLINE	Fresenius Kabi	marketed	Tetracycline-class Antibacterial [EPC]	30S ribosomal subunit	2005-01-01
CHLORTETRACYCLINE HYDROCHLORIDE	CHLORTETRACYCLINE HYDROCHLORIDE		marketed	Tetracycline	30S ribosomal subunit	1950-01-01
Usual doses of tigecycline	Usual doses of tigecycline	Air Force Specialized Hospital, Cairo, Egypt	marketed	Tetracycline antibiotic	Bacterial 30S ribosomal subunit
Minocycline HCl	Minocycline HCl	OraPharma	marketed	Tetracycline antibiotic	Bacterial 30S ribosomal subunit
Gentamicin - three days	Gentamicin - three days	Murdoch Childrens Research Institute	marketed	Aminoglycoside antibiotic	Bacterial 30S ribosomal subunit
Doxycycline Hyclate Enteric-Coated Capsules	Doxycycline Hyclate Enteric-Coated Capsules	The Third Xiangya Hospital of Central South University	marketed	Tetracycline antibiotic	Bacterial 30S ribosomal subunit

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

• 2028-10-24 — Tygacil · 8975242 · US
• 2029-02-05 — Tygacil · 7879828 · US
• 2030-10-08 — Tygacil · 8372995 · US
• 2033-04-07 — Tygacil · 9855335 · US

Sponsor landscape (tetracycline antibiotic class)

1. BioPharmX, Inc. · 2 drugs in this class
2. Hospital General de Mexicali · 1 drug in this class
3. Laboratorios Goulart S.A. · 1 drug in this class
4. National Taiwan University Hospital · 1 drug in this class