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BPaL — Competitive Intelligence Brief
phase 3
Antituberculous combination therapy
Mycobacterial ATP synthase (bedaquiline), mycobacterial DNA/proteins (pretomanid), bacterial ribosome (linezolid)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
BPaL (BPaL) — Otsuka Pharmaceutical Development & Commercialization, Inc.. BPaL is a three-drug combination regimen (bedaquiline, pretomanid, and linezolid) that inhibits mycobacterial ATP synthase and protein synthesis to kill drug-resistant tuberculosis bacteria.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BPaL TARGET | BPaL | Otsuka Pharmaceutical Development & Commercialization, Inc. | phase 3 | Antituberculous combination therapy | Mycobacterial ATP synthase (bedaquiline), mycobacterial DNA/proteins (pretomanid), bacterial ribosome (linezolid) | |
| MDR-TB Treatment Regimen(WHO) | MDR-TB Treatment Regimen(WHO) | Shanghai Pulmonary Hospital, Shanghai, China | marketed | Antituberculous combination therapy | ||
| New regimen(BdqCfzLzd+XY) | New regimen(BdqCfzLzd+XY) | Shanghai Pulmonary Hospital, Shanghai, China | marketed | Antituberculous combination therapy |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antituberculous combination therapy class)
- Shanghai Pulmonary Hospital, Shanghai, China · 2 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BPaL — Competitive Intelligence Brief. https://druglandscape.com/ci/bpal. Accessed 2026-05-15.
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