Who are BioNTech - Pfizer COVID-19 vaccine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Heterologous mRNA booster vaccine, Comirnaty Original/Omicron BA.4-5, Combination BNT162b2 and BNT162b2 OMI, BNT162b5 Bivalent (Original/OMI BA.4/BA.5), bivalent BNT162b2 (original/Omi BA.4/BA.5), Homologous mRNA booster vaccine.

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Last reviewed 2026-05-16 · How we verify

BioNTech - Pfizer COVID-19 vaccine — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

BioNTech - Pfizer COVID-19 vaccine (BioNTech - Pfizer COVID-19 vaccine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: mRNA vaccine. Area: Immunology / Infectious Disease.

marketed mRNA vaccine SARS-CoV-2 spike protein (S protein) Immunology / Infectious Disease Biologic Live · refreshed every 30 min

Target snapshot

BioNTech - Pfizer COVID-19 vaccine (BioNTech - Pfizer COVID-19 vaccine) — University of Birmingham. This mRNA vaccine instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response that protects against COVID-19 infection.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
BioNTech - Pfizer COVID-19 vaccine TARGET	BioNTech - Pfizer COVID-19 vaccine	University of Birmingham	marketed	mRNA vaccine	SARS-CoV-2 spike protein (S protein)
Heterologous mRNA booster vaccine	Heterologous mRNA booster vaccine	Tan Tock Seng Hospital	marketed	mRNA vaccine
Comirnaty Original/Omicron BA.4-5	Comirnaty Original/Omicron BA.4-5	Jules Bordet Institute	marketed	mRNA vaccine	SARS-CoV-2 spike protein (original strain and Omicron BA.4-5 variants)
Combination BNT162b2 and BNT162b2 OMI	combination-bnt162b2-and-bnt162b2-omi	Pfizer	marketed	mRNA vaccine	SARS-CoV-2 spike protein
BNT162b5 Bivalent (Original/OMI BA.4/BA.5)	bnt162b5-bivalent-original-omi-ba-4-ba-5	Pfizer	marketed	mRNA vaccine	Spike protein of SARS-CoV-2
bivalent BNT162b2 (original/Omi BA.4/BA.5)	bivalent-bnt162b2-original-omi-ba-4-ba-5	Pfizer	marketed	mRNA vaccine	SARS-CoV-2 virus
Homologous mRNA booster vaccine	Homologous mRNA booster vaccine	Tan Tock Seng Hospital	marketed	mRNA vaccine

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (mRNA vaccine class)

Pfizer · 12 drugs in this class
ModernaTX, Inc. · 11 drugs in this class
BioNTech SE · 5 drugs in this class
Jules Bordet Institute · 5 drugs in this class
Tan Tock Seng Hospital · 2 drugs in this class
Clover Biopharmaceuticals AUS Pty · 1 drug in this class
CanSino Biologics Inc. · 1 drug in this class
Assistance Publique - Hôpitaux de Paris · 1 drug in this class
CSPC Megalith Biopharmaceutical Co.,Ltd. · 1 drug in this class
Jens D Lundgren, MD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). BioNTech - Pfizer COVID-19 vaccine — Competitive Intelligence Brief. https://druglandscape.com/ci/biontech-pfizer-covid-19-vaccine. Accessed 2026-05-16.

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