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BGB-A445 — Competitive Intelligence Brief
phase 3
Bcl-2 inhibitor
Bcl-2
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
BGB-A445 (BGB-A445) — BeiGene. BGB-A445 is a Bcl-2 inhibitor that promotes apoptosis in cancer cells by blocking anti-apoptotic proteins.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BGB-A445 TARGET | BGB-A445 | BeiGene | phase 3 | Bcl-2 inhibitor | Bcl-2 | |
| Venetoclax; Rituximab | venetoclax-rituximab | Pfizer | marketed | BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) | BCL-2 (venetoclax); CD20 (rituximab) | N/A |
| Venclexta | venetoclax | AbbVie | marketed | BCL-2 Inhibitor [EPC] | Apoptosis regulator Bcl-2 | 2014-01-01 |
| Ixempra Kit | IXABEPILONE | R-Pharm Us Llc | marketed | Microtubule Inhibitor | Apoptosis regulator Bcl-2 | 2007-01-01 |
| Venetoclax (VEN) | Venetoclax (VEN) | Nanfang Hospital, Southern Medical University | marketed | BCL-2 inhibitor | BCL-2 | |
| VEN | VEN | Janssen Research & Development, LLC | marketed | BCL-2 inhibitor | BCL-2 | |
| Perazyl | CHLORCYCLIZINE | marketed | chlorcyclizine | Apoptosis regulator Bcl-2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Venclexta · 9174982 · US
- — Venclexta · 8546399 · US
- — Venclexta · 10730873 · US
- — Venclexta · 8722657 · US
- — Venclexta · 11369599 · US
- — Venclexta · 11110087 · US
- — Venclexta · 11590128 · US
- — Venclexta · 10993942 · US
- — Venclexta · 9539251 · US
- — Venclexta · 11413282 · US
Sponsor landscape (Bcl-2 inhibitor class)
- BeiGene · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BGB-A445 — Competitive Intelligence Brief. https://druglandscape.com/ci/bgb-a445. Accessed 2026-05-14.
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