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BF-200 ALA 10% — Competitive Intelligence Brief
phase 2
Photodynamic therapy agent
Protoporphyrin IX (photosensitizer)
Dermatology/Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
BF-200 ALA 10% (BF-200 ALA 10%) — Biofrontera Bioscience GmbH. BF-200 ALA is a topical 5-aminolevulinic acid (ALA) formulation that generates reactive oxygen species upon light activation to destroy abnormal skin cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BF-200 ALA 10% TARGET | BF-200 ALA 10% | Biofrontera Bioscience GmbH | phase 2 | Photodynamic therapy agent | Protoporphyrin IX (photosensitizer) | |
| Ameluz 10% Topical Gel | Ameluz 10% Topical Gel | Psoriasis Treatment Center of Central New Jersey | marketed | Photodynamic therapy agent | Protoporphyrin IX (photosensitizer) | |
| TOOKAD VTP | TOOKAD VTP | Steba Biotech S.A. | marketed | Photodynamic therapy agent | Vascular endothelial cells (non-receptor mediated phototoxicity) | |
| BF-200 ALA cream | BF-200 ALA cream | Joint Authority for Päijät-Häme Social and Health Care | marketed | Photodynamic therapy agent | Protoporphyrin IX (photosensitizer generated from aminolevulinic acid) | |
| Physician's Choice SOC | Physician's Choice SOC | Rakuten Medical, Inc. | phase 3 | X-ray activated photodynamic therapy agent | ||
| c-PDT | c-PDT | Galderma R&D | phase 3 | Photodynamic therapy agent | ||
| NDL-PDT | NDL-PDT | Galderma R&D | phase 3 | Photodynamic therapy agent |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Photodynamic therapy agent class)
- Galderma R&D · 3 drugs in this class
- DUSA Pharmaceuticals, Inc. · 2 drugs in this class
- Biofrontera Bioscience GmbH · 2 drugs in this class
- Steba Biotech S.A. · 2 drugs in this class
- National Cancer Center, Korea · 1 drug in this class
- Photocure · 1 drug in this class
- Psoriasis Treatment Center of Central New Jersey · 1 drug in this class
- Joint Authority for Päijät-Häme Social and Health Care · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BF-200 ALA 10% — Competitive Intelligence Brief. https://druglandscape.com/ci/bf-200-ala-10. Accessed 2026-06-10.
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