Who are BEROTRALSTAT HYDROCHLORIDE's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Orladeyo, Takhzyro, Kalbitor, C1 Esterase Inhibitor (Human), TAKHZYRO, BCX7353 capsules.

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Last reviewed 2026-06-10 · How we verify

BEROTRALSTAT HYDROCHLORIDE — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

BEROTRALSTAT HYDROCHLORIDE (BEROTRALSTAT HYDROCHLORIDE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline.

marketed plasma kallikrein Small molecule Live · refreshed every 30 min

Target snapshot

BEROTRALSTAT HYDROCHLORIDE (BEROTRALSTAT HYDROCHLORIDE). Berotralstat inhibits plasma kallikrein to reduce bradykinin generation and control angioedema in HAE.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
BEROTRALSTAT HYDROCHLORIDE TARGET	BEROTRALSTAT HYDROCHLORIDE		marketed		plasma kallikrein	2020-01-01
Orladeyo	BEROTRALSTAT	Biocryst	marketed	Plasma Kallikrein Inhibitor	Plasma kallikrein	2020-01-01
Takhzyro	LANADELUMAB	Dyax Corp	marketed	Plasma Kallikrein Inhibitor [EPC]	plasma kallikrein	2018-01-01
Kalbitor	ECALLANTIDE	Dyax Corp.	marketed	Plasma Kallikrein Inhibitor [EPC]	Plasma kallikrein	2009-01-01
C1 Esterase Inhibitor (Human)	C1 Esterase Inhibitor (Human)	Shire	marketed	Serine protease inhibitor; complement regulator	C1 esterase inhibitor (C1-INH); Factor XIIa; plasma kallikrein
TAKHZYRO	LANADELUMAB-FLYO	DYAX CORP.	marketed	Plasma Kallikrein Inhibitor [EPC]	Plasma kallikrein
BCX7353 capsules	BCX7353 capsules	BioCryst Pharmaceuticals	phase 3	Plasma kallikrein inhibitor	Plasma kallikrein (Factor XIa)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape

No sponsor landscape data.

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Cite this brief

Drug Landscape (2026). BEROTRALSTAT HYDROCHLORIDE — Competitive Intelligence Brief. https://druglandscape.com/ci/berotralstat-hydrochloride. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing