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BERLIM 25/10 association — Competitive Intelligence Brief

BERLIM 25/10 association (BERLIM 25/10 association) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Angiotensin II receptor antagonist + thiazide diuretic combination. Area: Cardiovascular.

phase 3 Angiotensin II receptor antagonist + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); thiazide-sensitive sodium-chloride cotransporter Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

BERLIM 25/10 association (BERLIM 25/10 association) — EMS. BERLIM 25/10 is a fixed-dose combination of losartan (angiotensin II receptor antagonist) and hydrochlorothiazide (thiazide diuretic) that reduces blood pressure through dual antihypertensive pathways.

Comparator set (3 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
BERLIM 25/10 association TARGET BERLIM 25/10 association EMS phase 3 Angiotensin II receptor antagonist + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); thiazide-sensitive sodium-chloride cotransporter
hydrochlorothiazide, losartan hydrochlorothiazide, losartan University Hospital, Strasbourg, France marketed Angiotensin II receptor antagonist + thiazide diuretic combination AT1 receptor (losartan); sodium-chloride cotransporter (hydrochlorothiazide)
BERLIM 25/20 ASSOCIATION BERLIM 25/20 ASSOCIATION EMS phase 3 Angiotensin II receptor antagonist + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); thiazide-sensitive sodium-chloride cotransporter
Losartan + hydrochlorothiazide in fixed dose Losartan + hydrochlorothiazide in fixed dose Laboratorios Silanes S.A. de C.V. phase 3 Angiotensin II receptor antagonist + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Angiotensin II receptor antagonist + thiazide diuretic combination class)

  1. EMS · 2 drugs in this class
  2. Laboratorios Silanes S.A. de C.V. · 1 drug in this class
  3. University Hospital, Strasbourg, France · 1 drug in this class

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Cite this brief

Drug Landscape (2026). BERLIM 25/10 association — Competitive Intelligence Brief. https://druglandscape.com/ci/berlim-25-10-association. Accessed 2026-05-16.

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