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BEP(500) — Competitive Intelligence Brief
phase 3
Bispecific antibody
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
BEP(500) (BEP(500)) — Institute of Cancer Research, United Kingdom. BEP(500) is a bispecific antibody that simultaneously engages two distinct molecular targets to enhance anti-tumor immune responses.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BEP(500) TARGET | BEP(500) | Institute of Cancer Research, United Kingdom | phase 3 | Bispecific antibody | ||
| Elrexfio | elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrexfio | Elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrantamab | elrantamab | Pfizer | marketed | Bispecific Antibody | BCMA (B-cell maturation antigen) | |
| Mosunetuzumab (SC) | Mosunetuzumab (SC) | The Lymphoma Academic Research Organisation | phase 3 | Bispecific antibody (T-cell engager) | CD20 and CD3 | |
| SAR408701 | SAR408701 | Sanofi | phase 3 | Bispecific antibody; CD40/4-1BB agonist | CD40 and 4-1BB (TNFRSF9) | |
| KN046 | KN046 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | phase 3 | Bispecific antibody; PD-L1/4-1BB bispecific immune checkpoint modulator | PD-L1 and 4-1BB |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific antibody class)
- Shanghai Miracogen Inc. · 3 drugs in this class
- Atom Therapeutics Co., Ltd · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Allergan · 1 drug in this class
- AstraZeneca · 1 drug in this class
- BioNTech SE · 1 drug in this class
- DualityBio Inc. · 1 drug in this class
- Coherus Oncology, Inc. · 1 drug in this class
- Genmab · 1 drug in this class
- Amgen · 1 drug in this class
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- BEP(500) CI watch — RSS
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- BEP(500) alone — RSS
- Whole Bispecific antibody class — RSS
Cite this brief
Drug Landscape (2026). BEP(500) — Competitive Intelligence Brief. https://druglandscape.com/ci/bep-500. Accessed 2026-05-14.
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