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Benzyl penicillin — Competitive Intelligence Brief
phase 3
Beta-lactam antibiotic
Penicillin-binding proteins (PBPs)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Benzyl penicillin (Benzyl penicillin) — KEMRI-Wellcome Trust Collaborative Research Program. Benzyl penicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Benzyl penicillin TARGET | Benzyl penicillin | KEMRI-Wellcome Trust Collaborative Research Program | phase 3 | Beta-lactam antibiotic | Penicillin-binding proteins (PBPs) | |
| Amoxil | amoxicillin | Generic (originally Beecham/GSK) | marketed | Aminopenicillin (Beta-lactam antibiotic) | 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C | 1972-01-01 |
| Bicillin C-R | Penicillin G Benzathine | Pfizer | marketed | Beta-lactam antibiotic | Cell-wall peptidoglycan biosynthesis | 1952-01-01 |
| Bicillin C-R | Penicillin G Benzathine | Pfizer | marketed | Beta-lactam antibiotic | Cell-wall peptidoglycan biosynthesis | 1952-01-01 |
| Antibiotics, cefuroxime and metronidazole | Antibiotics, cefuroxime and metronidazole | Helsinki University Central Hospital | marketed | Beta-lactam antibiotic + nitroimidazole antibiotic combination | Bacterial penicillin-binding proteins (cefuroxime); anaerobic bacterial DNA (metronidazole) | |
| Amoxicillin and Clavulanic Acid | Amoxicillin and Clavulanic Acid | Maggiore Bellaria Hospital, Bologna | marketed | Beta-lactam antibiotic with beta-lactamase inhibitor | Penicillin-binding proteins (PBPs); bacterial beta-lactamases | |
| Piperacillin / Tazobactam Injection | Piperacillin / Tazobactam Injection | Rambam Health Care Campus | marketed | Beta-lactam antibiotic with beta-lactamase inhibitor | Penicillin-binding proteins; bacterial beta-lactamase enzymes |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Amoxil · 8778924 · Compound · US
- — Amoxil · 8357394 · Formulation · US
- — Amoxil · 8299052 · Method of Use · US
Sponsor landscape (Beta-lactam antibiotic class)
- Pfizer · 2 drugs in this class
- Bayer · 1 drug in this class
- Belén Retamal-Valdes · 1 drug in this class
- Benova (Tianjin) Innovative medicine Research Co., Ltd. · 1 drug in this class
- Esraa Salah Mohamed Abdallah Eladl · 1 drug in this class
- Incheon St.Mary's Hospital · 1 drug in this class
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group · 1 drug in this class
- KEMRI-Wellcome Trust Collaborative Research Program · 1 drug in this class
- National Taiwan University Hospital · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Benzyl penicillin — Competitive Intelligence Brief. https://druglandscape.com/ci/benzyl-penicillin. Accessed 2026-06-09.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing