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BAY60-4552 plus Vardenafil — Competitive Intelligence Brief
phase 2
Soluble guanylate cyclase activator + phosphodiesterase-5 inhibitor combination
Soluble guanylate cyclase (sGC) and phosphodiesterase-5 (PDE-5)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
BAY60-4552 plus Vardenafil (BAY60-4552 plus Vardenafil) — Bayer. BAY60-4552 activates soluble guanylate cyclase to increase cGMP levels, while vardenafil inhibits phosphodiesterase-5 to prevent cGMP degradation, synergistically enhancing vasodilation and improving erectile function.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BAY60-4552 plus Vardenafil TARGET | BAY60-4552 plus Vardenafil | Bayer | phase 2 | Soluble guanylate cyclase activator + phosphodiesterase-5 inhibitor combination | Soluble guanylate cyclase (sGC) and phosphodiesterase-5 (PDE-5) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Soluble guanylate cyclase activator + phosphodiesterase-5 inhibitor combination class)
- Bayer · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BAY60-4552 plus Vardenafil — Competitive Intelligence Brief. https://druglandscape.com/ci/bay60-4552-plus-vardenafil. Accessed 2026-05-16.
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