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Baxdrostat/dapagliflozin — Competitive Intelligence Brief
phase 3
Aldosterone synthase inhibitor + SGLT2 inhibitor combination
CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2)
Cardiovascular, Nephrology
Small molecule
Live · refreshed every 30 min
Target snapshot
Baxdrostat/dapagliflozin (Baxdrostat/dapagliflozin) — AstraZeneca. Baxdrostat inhibits aldosterone synthase to reduce aldosterone production, while dapagliflozin inhibits SGLT2 to increase urinary glucose excretion and reduce sodium reabsorption.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Baxdrostat/dapagliflozin TARGET | Baxdrostat/dapagliflozin | AstraZeneca | phase 3 | Aldosterone synthase inhibitor + SGLT2 inhibitor combination | CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2) | |
| Baxdrostat and dapagliflozin | Baxdrostat and dapagliflozin | AstraZeneca | phase 3 | Aldosterone synthase inhibitor + SGLT2 inhibitor combination | CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Aldosterone synthase inhibitor + SGLT2 inhibitor combination class)
- AstraZeneca · 2 drugs in this class
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- Baxdrostat/dapagliflozin CI watch — RSS
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Cite this brief
Drug Landscape (2026). Baxdrostat/dapagliflozin — Competitive Intelligence Brief. https://druglandscape.com/ci/baxdrostat-dapagliflozin. Accessed 2026-05-16.
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