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Baxdrostat/dapagliflozin — Competitive Intelligence Brief

Baxdrostat/dapagliflozin (Baxdrostat/dapagliflozin) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Aldosterone synthase inhibitor + SGLT2 inhibitor combination. Area: Cardiovascular, Nephrology.

phase 3 Aldosterone synthase inhibitor + SGLT2 inhibitor combination CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2) Cardiovascular, Nephrology Small molecule Live · refreshed every 30 min

Target snapshot

Baxdrostat/dapagliflozin (Baxdrostat/dapagliflozin) — AstraZeneca. Baxdrostat inhibits aldosterone synthase to reduce aldosterone production, while dapagliflozin inhibits SGLT2 to increase urinary glucose excretion and reduce sodium reabsorption.

Comparator set (1 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Baxdrostat/dapagliflozin TARGET Baxdrostat/dapagliflozin AstraZeneca phase 3 Aldosterone synthase inhibitor + SGLT2 inhibitor combination CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2)
Baxdrostat and dapagliflozin Baxdrostat and dapagliflozin AstraZeneca phase 3 Aldosterone synthase inhibitor + SGLT2 inhibitor combination CYP11B2 (aldosterone synthase) and SGLT2 (sodium-glucose cotransporter 2)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Aldosterone synthase inhibitor + SGLT2 inhibitor combination class)

  1. AstraZeneca · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Baxdrostat/dapagliflozin — Competitive Intelligence Brief. https://druglandscape.com/ci/baxdrostat-dapagliflozin. Accessed 2026-05-16.

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