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AZT — Competitive Intelligence Brief
marketed
Nucleoside reverse transcriptase inhibitor (NRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
AZT (AZT) — Johns Hopkins Bloomberg School of Public Health. AZT (zidovudine) inhibits HIV reverse transcriptase, preventing the virus from converting its RNA genome into DNA and replicating within host cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AZT TARGET | AZT | Johns Hopkins Bloomberg School of Public Health | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| Doravirine, Tenofovir, Lamivudine | Doravirine, Tenofovir, Lamivudine | Merck Sharp & Dohme LLC | marketed | Antiretroviral combination (NNRTI + NRTIs) | HIV reverse transcriptase, HIV integrase | |
| Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir | Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir | St Stephens Aids Trust | marketed | Antiretroviral agents (INSTI, NNRTI, NRTI/NtRTI) | HIV integrase (dolutegravir); HIV reverse transcriptase (efavirenz and combination); HIV entry (tenofovir/emtricitabine component) | |
| Eviplera® | Eviplera® | St Stephens Aids Trust | marketed | Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase | |
| FTC/TAF | FTC/TAF | ViiV Healthcare | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor combination | HIV reverse transcriptase | |
| ZIAGEN® | ZIAGEN® | ViiV Healthcare | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| zidovudine+lamivudine+lopinavir/ritonavir | zidovudine+lamivudine+lopinavir/ritonavir | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | marketed | Antiretroviral combination therapy (NRTI + PI) | HIV reverse transcriptase and HIV protease |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleoside reverse transcriptase inhibitor (NRTI) class)
- French National Agency for Research on AIDS and Viral Hepatitis · 3 drugs in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- ViiV Healthcare · 2 drugs in this class
- Nanfang Hospital, Southern Medical University · 2 drugs in this class
- Asan Medical Center · 1 drug in this class
- Dong-A ST Co., Ltd. · 1 drug in this class
- Bristol-Myers Squibb · 1 drug in this class
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
- Fu-Sheng Wang · 1 drug in this class
- Avexa · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AZT — Competitive Intelligence Brief. https://druglandscape.com/ci/azt. Accessed 2026-05-13.
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