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AZD7442 — Competitive Intelligence Brief
phase 3
Monoclonal antibody combination
SARS-CoV-2 spike protein receptor-binding domain
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
AZD7442 (AZD7442) — AstraZeneca. AZD7442 is a combination of two monoclonal antibodies that bind to the SARS-CoV-2 spike protein to neutralize the virus and provide passive immunity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AZD7442 TARGET | AZD7442 | AstraZeneca | phase 3 | Monoclonal antibody combination | SARS-CoV-2 spike protein receptor-binding domain | |
| Casirivimab and Imdevimab Drug Combination | Casirivimab and Imdevimab Drug Combination | Mansoura University Hospital | marketed | Monoclonal antibody combination (SARS-CoV-2 neutralizing antibodies) | SARS-CoV-2 spike protein receptor-binding domain | |
| Lilly Bamlanivimab + Etesevimab | Lilly Bamlanivimab + Etesevimab | Erin McCreary | marketed | Monoclonal antibody combination (neutralizing antibodies) | SARS-CoV-2 spike protein receptor-binding domain | |
| SCB-2019/Clover | SCB-2019/Clover | D'Or Institute for Research and Education | phase 3 | Recombinant protein vaccine | SARS-CoV-2 spike protein receptor-binding domain (RBD) | |
| BRII-196 | BRII-196 | National Institute of Allergy and Infectious Diseases (NIAID) | phase 3 | Monoclonal antibody (neutralizing) | SARS-CoV-2 spike protein receptor-binding domain (RBD) | |
| BRII-196/BRII-198 | BRII-196/BRII-198 | National Institute of Allergy and Infectious Diseases (NIAID) | phase 3 | Monoclonal antibody combination | SARS-CoV-2 spike protein receptor-binding domain | |
| daclizumab, infliximab | daclizumab, infliximab | University of Iowa | marketed | Monoclonal antibody combination | IL-2 receptor alpha (CD25) and TNF-alpha |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody combination class)
- AstraZeneca · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- The First People's Hospital of Changzhou · 1 drug in this class
- University of Iowa · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AZD7442 — Competitive Intelligence Brief. https://druglandscape.com/ci/azd7442. Accessed 2026-05-13.
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