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AZD5148 — Competitive Intelligence Brief
phase 2
adenosine A2A receptor antagonist
A2A receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
AZD5148 (AZD5148) — AstraZeneca. AZD5148 is a selective, potent and orally bioavailable adenosine A2A receptor antagonist.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AZD5148 TARGET | AZD5148 | AstraZeneca | phase 2 | adenosine A2A receptor antagonist | A2A receptor | |
| SG | SG | Arcus Biosciences, Inc. | marketed | Adenosine 2A receptor antagonist | A2A receptor (adenosine 2A receptor) | |
| Regadenoson (Lexiscan) | Regadenoson (Lexiscan) | Brigham and Women's Hospital | marketed | Adenosine A2A receptor agonist | Adenosine A2A receptor | |
| Regadenoson MRI myocardial blood flow | Regadenoson MRI myocardial blood flow | University of Colorado, Denver | marketed | Adenosine A2A receptor agonist | Adenosine A2A receptor | |
| Regadenoson myocardial perfusion imaging | Regadenoson myocardial perfusion imaging | University of Colorado, Denver | marketed | Adenosine A2A receptor agonist | Adenosine A2A receptor | |
| Regadenoson peripheral - peripheral | Regadenoson peripheral - peripheral | Lokien van Nunen | phase 3 | Adenosine A2A receptor agonist | Adenosine A2A receptor | |
| Regadenoson peripheral - central | Regadenoson peripheral - central | Lokien van Nunen | phase 3 | Adenosine A2A receptor agonist | Adenosine A2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (adenosine A2A receptor antagonist class)
- AstraZeneca · 3 drugs in this class
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Cite this brief
Drug Landscape (2026). AZD5148 — Competitive Intelligence Brief. https://druglandscape.com/ci/azd5148. Accessed 2026-05-13.
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