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Azathioprine (AZA) — Competitive Intelligence Brief
marketed
Purine analog immunosuppressant
Inosine monophosphate dehydrogenase (IMPDH), purine synthesis pathway
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Azathioprine (AZA) (Azathioprine (AZA)) — University Hospital Schleswig-Holstein. Azathioprine is a purine analog prodrug that is converted to 6-mercaptopurine, which inhibits purine synthesis and suppresses T-cell and B-cell proliferation.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Azathioprine (AZA) TARGET | Azathioprine (AZA) | University Hospital Schleswig-Holstein | marketed | Purine analog immunosuppressant | Inosine monophosphate dehydrogenase (IMPDH), purine synthesis pathway | |
| Azathioprine / 6 Mercaptopurine | Azathioprine / 6 Mercaptopurine | PIBD-Net | marketed | Purine analog immunosuppressant | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), inosine monophosphate dehydrogenase (IMPDH) | |
| addition of azathioprine | addition of azathioprine | Védrines, Philippe, M.D. | marketed | Purine analog immunosuppressant | Inosine monophosphate dehydrogenase (IMPDH), hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Purine analog immunosuppressant class)
- PIBD-Net · 1 drug in this class
- University Hospital Schleswig-Holstein · 1 drug in this class
- Védrines, Philippe, M.D. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Azathioprine (AZA) — Competitive Intelligence Brief. https://druglandscape.com/ci/azathioprine-aza. Accessed 2026-05-16.
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