Who are AVT04's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Bevacizumab (Avastin®), Bevacizumab (Bev), Subconjunctival Bevacizumab, Intravitreal bevacizumab, Intravitreal injection of bevacizumab, Intravitreal Bevacizumab IVB.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

AVT04 — Competitive Intelligence Brief

AVT04 (AVT04) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: VEGF inhibitor (monoclonal antibody); biosimilar. Area: Oncology.

phase 3 VEGF inhibitor (monoclonal antibody); biosimilar VEGF (Vascular Endothelial Growth Factor) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

AVT04 (AVT04) — Alvotech Swiss AG. AVT04 is a biosimilar of bevacizumab that inhibits vascular endothelial growth factor (VEGF) to block tumor angiogenesis and reduce blood supply to cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
AVT04 TARGET	AVT04	Alvotech Swiss AG	phase 3	VEGF inhibitor (monoclonal antibody); biosimilar	VEGF (Vascular Endothelial Growth Factor)
Bevacizumab (Avastin®)	Bevacizumab (Avastin®)	Hanny Al-Samkari, MD	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (Vascular Endothelial Growth Factor)
Bevacizumab (Bev)	Bevacizumab (Bev)	Eli Lilly and Company	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (Vascular Endothelial Growth Factor)
Subconjunctival Bevacizumab	Subconjunctival Bevacizumab	Grewal Eye Institute	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (Vascular Endothelial Growth Factor)
Intravitreal bevacizumab	Intravitreal bevacizumab	University of Sao Paulo	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (Vascular Endothelial Growth Factor)
Intravitreal injection of bevacizumab	Intravitreal injection of bevacizumab	Barnes Retina Institute	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (vascular endothelial growth factor)
Intravitreal Bevacizumab IVB	Intravitreal Bevacizumab IVB	Khyber Teaching Hospital	marketed	VEGF inhibitor (monoclonal antibody)	VEGF (Vascular Endothelial Growth Factor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (VEGF inhibitor (monoclonal antibody); biosimilar class)

Alvotech Swiss AG · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AVT04 — Competitive Intelligence Brief. https://druglandscape.com/ci/avt04. Accessed 2026-05-15.

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