Who are Augment with Memantine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Namenda, Felbatol, QUINIDINE, Methadone Hydrochloride, Esketamine Nasal Spray [Spravato], S-Ketamine 0.75.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Augment with Memantine — Competitive Intelligence Brief

Augment with Memantine (Augment with Memantine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NMDA receptor antagonist. Area: Neurology.

phase 2 NMDA receptor antagonist NMDA receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Augment with Memantine (Augment with Memantine) — Shanghai Mental Health Center. Augment with Memantine is a combination of a glutamate receptor antagonist and a NMDA receptor antagonist, which may help to improve cognitive function in patients with Alzheimer's disease.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Augment with Memantine TARGET	Augment with Memantine	Shanghai Mental Health Center	phase 2	NMDA receptor antagonist	NMDA receptor
Namenda	MEMANTINE	AbbVie	marketed	N-methyl-D-aspartate Receptor Antagonist	Glutamate NMDA receptor; GRIN1/GRIN2A	2003-01-01
Felbatol	FELBAMATE	Mylan Speciality Lp	marketed	Anti-epileptic Agent [EPC]	NMDA receptor-ionophore complex	1993-01-01
QUINIDINE	QUINIDINE		marketed		sigma-1 receptor, NMDA receptor, CYP2D6	1950-01-01
Methadone Hydrochloride	METHADONE	Specgx Llc	marketed	Opioid Agonist	mu-opioid receptors, NMDA receptor	1947-01-01
Esketamine Nasal Spray [Spravato]	Esketamine Nasal Spray [Spravato]	Royal North Shore Hospital	marketed	NMDA receptor antagonist	NMDA receptor
S-Ketamine 0.75	S-Ketamine 0.75	Turku University Hospital	marketed	NMDA receptor antagonist	NMDA receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NMDA receptor antagonist class)

Turku University Hospital · 3 drugs in this class
H. Lundbeck A/S · 2 drugs in this class
Ciusss de L'Est de l'Île de Montréal · 2 drugs in this class
Shalvata Mental Health Center · 2 drugs in this class
New York State Psychiatric Institute · 2 drugs in this class
Auris Medical AG · 1 drug in this class
AstraZeneca · 1 drug in this class
Alameda Health System · 1 drug in this class
Centre Hospitalier Universitaire de Nice · 1 drug in this class
Asker & Baerum Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Augment with Memantine — Competitive Intelligence Brief. https://druglandscape.com/ci/augment-with-memantine. Accessed 2026-05-13.

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