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ATX101 — Competitive Intelligence Brief
phase 2
sodium-activated potassium channel inhibitor
Nav1.5
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
ATX101 (ATX101) — Aurobac Therapeutics SAS. ATX101 is a small molecule that acts as a selective inhibitor of the sodium-activated potassium channel, Nav1.5.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ATX101 TARGET | ATX101 | Aurobac Therapeutics SAS | phase 2 | sodium-activated potassium channel inhibitor | Nav1.5 | |
| Propafenone i.v. | Propafenone i.v. | Charles University, Czech Republic | marketed | Class IC antiarrhythmic agent | Cardiac sodium channel (Nav1.5) | |
| Medium-dose anrikefon | Medium-dose anrikefon | Peking University First Hospital | marketed | Sodium channel blocker | Nav1.5 | |
| Flecainide controlled release | Flecainide controlled release | MEDA Pharma GmbH & Co. KG | marketed | Class IC antiarrhythmic agent | Cardiac voltage-gated sodium channel (Nav1.5) | |
| Oral Capsule Mexiletine (IR) | Oral Capsule Mexiletine (IR) | Lupin Ltd. | phase 3 | Class IB antiarrhythmic agent | Cardiac voltage-gated sodium channel (Nav1.5) | |
| TV-46000 | TV-46000 | Teva Branded Pharmaceutical Products R&D, Inc. | phase 3 | Sodium-activated potassium channel inhibitor | Nav1.5 | |
| Flecainide Injectable Solution | Flecainide Injectable Solution | Hippocration General Hospital | phase 3 | Class IC antiarrhythmic agent | Cardiac voltage-gated sodium channel (Nav1.5) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (sodium-activated potassium channel inhibitor class)
- Aurobac Therapeutics SAS · 1 drug in this class
- Kasr El Aini Hospital · 1 drug in this class
- Maimonides Medical Center · 1 drug in this class
- Pfizer · 1 drug in this class
- Teva Branded Pharmaceutical Products R&D, Inc. · 1 drug in this class
- Upsher-Smith Laboratories · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ATX101 — Competitive Intelligence Brief. https://druglandscape.com/ci/atx101. Accessed 2026-05-13.
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