Last reviewed · How we verify

AT-527 single dose — Competitive Intelligence Brief

AT-527 single dose (AT-527 single dose) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: nucleoside analog. Area: Infectious Disease.

phase 1 nucleoside analog viral RNA-dependent RNA polymerase Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

AT-527 single dose (AT-527 single dose) — Atea Pharmaceuticals, Inc.. AT-527 is a nucleoside analog that inhibits viral RNA-dependent RNA polymerase, thereby blocking viral replication.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AT-527 single dose TARGET AT-527 single dose Atea Pharmaceuticals, Inc. phase 1 nucleoside analog viral RNA-dependent RNA polymerase
Ribavirin "loading" dose given Ribavirin "loading" dose given Göteborg University marketed Nucleoside analog antiviral Viral RNA-dependent RNA polymerase; IMPDH (inosine monophosphate dehydrogenase)
D: Peg-interferon alpha-2a & Ribavirin D: Peg-interferon alpha-2a & Ribavirin Kaohsiung Medical University Chung-Ho Memorial Hospital marketed Antiviral combination therapy Interferon-alpha receptor (IFNAR); viral RNA-dependent RNA polymerase
pegylated interferon alpha 2a, ribavirin pegylated interferon alpha 2a, ribavirin Kaohsiung Medical University Chung-Ho Memorial Hospital marketed Antiviral combination therapy Interferon-alpha receptor (IFNAR); viral RNA-dependent RNA polymerase
standard treatment COVID-19 + Triazavirin standard treatment COVID-19 + Triazavirin Ain Shams University marketed Nucleoside analog antiviral Viral RNA-dependent RNA polymerase (RdRp)
Infergen and ribavirin Infergen and ribavirin Kadmon Corporation, LLC marketed Interferon alpha and nucleoside analog combination Interferon-alpha receptor (IFNAR); viral RNA-dependent RNA polymerase
E: Peg-interferon alpha-2a & Ribavirin E: Peg-interferon alpha-2a & Ribavirin Kaohsiung Medical University Chung-Ho Memorial Hospital marketed Antiviral combination therapy Interferon-alpha receptor; viral RNA-dependent RNA polymerase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (nucleoside analog class)

  1. Atea Pharmaceuticals, Inc. · 1 drug in this class
  2. Bausch & Lomb Incorporated · 1 drug in this class
  3. Medivir · 1 drug in this class
  4. Tarapeutics Science Inc. · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). AT-527 single dose — Competitive Intelligence Brief. https://druglandscape.com/ci/at-527-single-dose. Accessed 2026-05-14.

Build your own brief

Pick any drug + add comparators: