Last reviewed · How we verify
ASP8477 — Competitive Intelligence Brief
phase 2
CDK inhibitor
CDK9
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
ASP8477 (ASP8477) — Astellas Pharma Europe B.V.. ASP8477 is a small molecule that targets the CDK9 protein.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ASP8477 TARGET | ASP8477 | Astellas Pharma Europe B.V. | phase 2 | CDK inhibitor | CDK9 | |
| RO4917838 | RO4917838 | Hoffmann-La Roche | phase 3 | CDK9 inhibitor | CDK9 | |
| TPX-114 | TPX-114 | Tego Science, Inc. | phase 3 | CDK inhibitor | CDK9 | |
| Palbociclib in combination with AI | palbociclib-in-combination-with-ai | Pfizer | marketed | CDK inhibitor | CDK4/6 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CDK inhibitor class)
- Astellas Pharma Europe B.V. · 1 drug in this class
- Dyve Biosciences, Inc. · 1 drug in this class
- Pfizer · 1 drug in this class
- Shirley Vichy Wang · 1 drug in this class
- Tego Science, Inc. · 1 drug in this class
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- ASP8477 CI watch — RSS
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- Whole CDK inhibitor class — RSS
Cite this brief
Drug Landscape (2026). ASP8477 — Competitive Intelligence Brief. https://druglandscape.com/ci/asp8477. Accessed 2026-05-13.
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