Who are ASP1517's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Al(OH)3, BMS-986278, BMS-986205, Both deferoxamine mesylate and colchicine.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

ASP1517 — Competitive Intelligence Brief

ASP1517 (ASP1517) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NLRP3 inflammasome inhibitor. Area: Inflammation.

phase 2 NLRP3 inflammasome inhibitor NLRP3 Inflammation Small molecule Live · refreshed every 30 min

Target snapshot

ASP1517 (ASP1517) — Astellas Pharma Inc. ASP1517 is a selective and potent inhibitor of the NLRP3 inflammasome.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
ASP1517 TARGET	ASP1517	Astellas Pharma Inc	phase 2	NLRP3 inflammasome inhibitor	NLRP3
Al(OH)3	Al(OH)3	Janssen Vaccines & Prevention B.V.	phase 3	Vaccine adjuvant	NLRP3 inflammasome; antigen-presenting cells
BMS-986278	BMS-986278	Bristol-Myers Squibb	phase 3	NLRP3 inflammasome inhibitor	NLRP3
BMS-986205	BMS-986205	Bristol-Myers Squibb	phase 3	NLRP3 inflammasome inhibitor	NLRP3
Both deferoxamine mesylate and colchicine	Both deferoxamine mesylate and colchicine	The George Institute	phase 3	Iron chelator + anti-inflammatory combination	Labile iron (deferoxamine); microtubule polymerization and NLRP3 inflammasome (colchicine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NLRP3 inflammasome inhibitor class)

Bristol-Myers Squibb · 2 drugs in this class
Aquinox Pharmaceuticals (Canada) Inc. · 1 drug in this class
Astellas Pharma Inc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ASP1517 — Competitive Intelligence Brief. https://druglandscape.com/ci/asp1517. Accessed 2026-05-13.

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