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ASC22 — Competitive Intelligence Brief
phase 2
PD-L1 inhibitor
PD-L1
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
ASC22 (ASC22) — Ascletis Pharmaceuticals Co., Ltd.. ASC22 is a humanized monoclonal antibody that blocks the PD-L1 checkpoint, enhancing anti-tumor immune responses by preventing PD-L1 from binding to PD-1 and B7.1 on immune cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ASC22 TARGET | ASC22 | Ascletis Pharmaceuticals Co., Ltd. | phase 2 | PD-L1 inhibitor | PD-L1 | |
| DURVALUMAB | DURVALUMAB | marketed | Programmed Death Ligand-1 Blocker [EPC] | PD-L1 | 2017-01-01 | |
| AVELUMAB | AVELUMAB | marketed | Programmed Death Ligand-1 Blocker [EPC] | PD-L1 | 2017-01-01 | |
| AB | AB | GlaxoSmithKline | marketed | PD-L1 inhibitor | PD-L1 | |
| PD-1 / PD-L1 monoclonal antibody | PD-1 / PD-L1 monoclonal antibody | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | marketed | PD-1/PD-L1 inhibitor | PD-1 and/or PD-L1 | |
| Cisplatin / Carboplatin,Gemcitabine,Cindilimab | Cisplatin / Carboplatin,Gemcitabine,Cindilimab | People's Hospital of Quzhou | marketed | Combination chemotherapy with immune checkpoint inhibitor | DNA (platinum agents, gemcitabine); PD-L1 (cindilimab) | |
| Avelumab first-line maintenance | Avelumab first-line maintenance | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | marketed | PD-L1 inhibitor | PD-L1 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PD-L1 inhibitor class)
- Biocad · 13 drugs in this class
- Shanghai Henlius Biotech · 8 drugs in this class
- Celltrion · 5 drugs in this class
- Mabwell (Shanghai) Bioscience Co., Ltd. · 4 drugs in this class
- AstraZeneca · 4 drugs in this class
- Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · 2 drugs in this class
- Innovent Biologics (Suzhou) Co. Ltd. · 2 drugs in this class
- Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
- Shanghai Hengrui Pharmaceutical Co., Ltd. · 2 drugs in this class
- CStone Pharmaceuticals · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ASC22 — Competitive Intelligence Brief. https://druglandscape.com/ci/asc22. Accessed 2026-05-14.
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