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ART0380 — Competitive Intelligence Brief
phase 2
DNA repair inhibitor
DPC (DNA-protein crosslink) repair pathway
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
ART0380 (ART0380) — Artios Pharma Ltd. ART0380 is a DNA-protein crosslink (DPC) repair inhibitor that enhances the activity of DNA damaging agents by preventing cellular repair of crosslinks.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ART0380 TARGET | ART0380 | Artios Pharma Ltd | phase 2 | DNA repair inhibitor | DPC (DNA-protein crosslink) repair pathway | |
| O6-benzylguanine | O6-benzylguanine | Case Comprehensive Cancer Center | phase 3 | DNA repair inhibitor / Alkyltransferase inhibitor | O6-alkylguanine-DNA alkyltransferase (AGT) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (DNA repair inhibitor class)
- Artios Pharma Ltd · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ART0380 — Competitive Intelligence Brief. https://druglandscape.com/ci/art0380. Accessed 2026-05-13.
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