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ARQ-151 cream 0.05% — Competitive Intelligence Brief
phase 2
JAK1 inhibitor
JAK1
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
ARQ-151 cream 0.05% (ARQ-151 cream 0.05%) — Arcutis Biotherapeutics, Inc.. ARQ-151 is a selective Janus kinase 1 (JAK1) inhibitor that modulates cytokine signaling involved in inflammatory responses.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ARQ-151 cream 0.05% TARGET | ARQ-151 cream 0.05% | Arcutis Biotherapeutics, Inc. | phase 2 | JAK1 inhibitor | JAK1 | |
| Leqselvi | DEURUXOLITINIB | Sun Pharm Inds Inc | marketed | JAK1, JAK2, TYK2 | 2024-01-01 | |
| Cibinqo | Abrocitinib | Pfizer | marketed | Janus Kinase Inhibitor [EPC] | Tyrosine-protein kinase JAK1 | 2022-01-01 |
| Cibinqo | abrocitinib | Pfizer | marketed | Janus Kinase Inhibitor [EPC] | Tyrosine-protein kinase JAK1 | 2022-01-01 |
| ABROCITINIB | ABROCITINIB | marketed | Janus Kinase Inhibitor [EPC] | JAK1 | 2021-01-01 | |
| Jyseleca | FILGOTINIB | Gilead Sciences Ireland UC | marketed | Tyrosine-protein kinase JAK1 | 2020-01-01 | |
| Abrocitinib Suspension F6 | abrocitinib-suspension-f6 | Pfizer | marketed | JAK inhibitor | JAK1 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (JAK1 inhibitor class)
- AbbVie · 2 drugs in this class
- Arcutis Biotherapeutics, Inc. · 1 drug in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ARQ-151 cream 0.05% — Competitive Intelligence Brief. https://druglandscape.com/ci/arq-151-cream-0-05. Accessed 2026-05-16.
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