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Aripiprazole; Quetiapine — Competitive Intelligence Brief
marketed
Atypical antipsychotic combination
Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor
Psychiatry/Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Aripiprazole; Quetiapine (Aripiprazole; Quetiapine) — Taichung Veterans General Hospital. This is a combination of two atypical antipsychotics that work by blocking dopamine and serotonin receptors in the brain to reduce psychotic symptoms and stabilize mood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Aripiprazole; Quetiapine TARGET | Aripiprazole; Quetiapine | Taichung Veterans General Hospital | marketed | Atypical antipsychotic combination | Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor | |
| Intramuscular aripiprazole, olanzapine | Intramuscular aripiprazole, olanzapine | Veterans Medical Research Foundation | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor | |
| Methylphenidate, aripiprazole, and combination | Methylphenidate, aripiprazole, and combination | Tri-Service General Hospital | marketed | Stimulant and atypical antipsychotic combination | Dopamine transporter (DAT), norepinephrine transporter (NET), dopamine D2 receptor (partial agonist), serotonin 5-HT1A receptor | |
| Lithium carbonate + perospirone hydrochloride | Lithium carbonate + perospirone hydrochloride | Shanghai Mental Health Center | marketed | Mood stabilizer + atypical antipsychotic combination | Inositol monophosphatase, GSK-3 (lithium); dopamine D2 receptor, serotonin 5-HT2A receptor (perospirone) | |
| venlafaxine XR plus aripiprazole | venlafaxine XR plus aripiprazole | University of Pittsburgh | marketed | SNRI plus atypical antipsychotic combination | Serotonin transporter (SERT), norepinephrine transporter (NET), dopamine D2 receptor | |
| Lamotrigine + Aripiprazole | Lamotrigine + Aripiprazole | Otsuka Pharmaceutical Development & Commercialization, Inc. | marketed | Anticonvulsant/mood stabilizer + atypical antipsychotic combination | Voltage-gated sodium channels (lamotrigine); dopamine D2/D3 receptors (aripiprazole) | |
| Sertraline + Olanzapine | Sertraline + Olanzapine | Weill Medical College of Cornell University | marketed | SSRI + atypical antipsychotic combination | Serotonin transporter (SERT); dopamine D2 receptor; serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic combination class)
- Changhua Christian Hospital · 1 drug in this class
- Heinrich-Heine University, Duesseldorf · 1 drug in this class
- Taichung Veterans General Hospital · 1 drug in this class
- Xian-Janssen Pharmaceutical Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Aripiprazole; Quetiapine — Competitive Intelligence Brief. https://druglandscape.com/ci/aripiprazole-quetiapine. Accessed 2026-05-16.
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