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aripiprazole (Abilify) — Competitive Intelligence Brief

aripiprazole (Abilify) (aripiprazole (Abilify)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Atypical antipsychotic. Area: Psychiatry.

marketed Atypical antipsychotic Dopamine D2 receptor (partial agonist), Serotonin 5-HT1A receptor (partial agonist) Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

aripiprazole (Abilify) (aripiprazole (Abilify)) — Massachusetts General Hospital. Aripiprazole is a partial agonist at dopamine D2 and serotonin 5-HT1A receptors that stabilizes dopamine and serotonin neurotransmission in the brain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
aripiprazole (Abilify) TARGET aripiprazole (Abilify) Massachusetts General Hospital marketed Atypical antipsychotic Dopamine D2 receptor (partial agonist), Serotonin 5-HT1A receptor (partial agonist)
Lybalvi SAMIDORPHAN Alkermes Inc marketed Atypical Antipsychotic [EPC] Mu-type opioid receptor 2021-01-01
SAMIDORPHAN L-MALATE SAMIDORPHAN L-MALATE marketed Atypical Antipsychotic [EPC] dopamine and serotonin type 2 (5HT2) receptors, opioid receptors 2021-01-01
Caplyta LUMATEPERONE Intra-Cellular marketed Atypical Antipsychotic [EPC] 5-hydroxytryptamine receptor 2A 2019-01-01
Nuplazid PIMAVANSERIN Acadia Pharms Inc marketed Atypical Antipsychotic 5-hydroxytryptamine receptor 2A 2016-01-01
Rexulti BREXPIPRAZOLE Otsuka marketed Atypical Antipsychotic [EPC] D(2) dopamine receptor 2015-01-01
Vraylar CARIPRAZINE AbbVie marketed Atypical Antipsychotic [EPC] D(3) dopamine receptor 2015-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Atypical antipsychotic class)

  1. Shanghai Mental Health Center · 10 drugs in this class
  2. AstraZeneca · 6 drugs in this class
  3. Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
  4. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
  5. Eli Lilly and Company · 4 drugs in this class
  6. Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
  7. Medical University of Vienna · 2 drugs in this class
  8. Organon and Co · 2 drugs in this class
  9. Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
  10. H. Lundbeck A/S · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). aripiprazole (Abilify) — Competitive Intelligence Brief. https://druglandscape.com/ci/aripiprazole-abilify. Accessed 2026-05-13.

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