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Abilify — Competitive Intelligence Brief
marketed
Third-generation antipsychotic (D2 partial agonist)
5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Abilify (aripiprazole) — Generic (originally Otsuka/BMS). Third-generation antipsychotic that acts as a partial agonist at D2 and 5-HT1A receptors, stabilizing dopamine activity rather than simply blocking it.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Abilify TARGET | aripiprazole | Generic (originally Otsuka/BMS) | marketed | Third-generation antipsychotic (D2 partial agonist) | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | 2002-11-15 |
| Risperdal | risperidone | Johnson & Johnson (Janssen) | marketed | Atypical Antipsychotic [EPC] | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | 1993-12-29 |
| Delysid | LYSERGIDE | marketed | lysergide | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | ||
| Abilify | Abilify | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | marketed | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | ||
| Ergot | Ergot | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | marketed | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | ||
| Risperdal | Risperdal | Ohio State University | marketed | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Risperdal · 10406160 · Formulation · US
- — Abilify · 9125939 · Method of Use · US
- — Abilify · 7978064 · Formulation · US
- — Risperdal · 9597402 · Formulation · US
- — Risperdal · 10058554 · Method of Use · US
- — Risperdal · 11110093 · Formulation · US
- — Abilify · 8759350 · Method of Use · US
- — Risperdal · 8741327 · Formulation · US
- — Risperdal · 8221778 · Formulation · US
- — Abilify · 9444503 · Formulation · US
- — Risperdal · 11712475 · Method of Use · US
- — Risperdal · 10010612 · Formulation · US
- — Risperdal · 9180197 · Formulation · US
- — Risperdal · 11013809 · Formulation · US
- — Risperdal · 10376590 · Method of Use · US
- — Risperdal · 9186413 · Method of Use · US
- — Abilify · 9119554 · Formulation · US
- — Abilify · 9258035 · Formulation · US
- — Abilify · 9060708 · Formulation · US
- — Abilify · 8674825 · Formulation · US
- — Abilify · 8956288 · Formulation · US
- — Abilify · 10441194 · Formulation · US
- — Abilify · 8945005 · Formulation · US
- — Abilify · 9433371 · Formulation · US
- — Abilify · 8718193 · Formulation · US
- — Abilify · 9149577 · Formulation · US
- — Abilify · 8847766 · Formulation · US
- — Abilify · 8545402 · Formulation · US
- — Abilify · 8114021 · Formulation · US
- — Abilify · 11464423 · Formulation · US
Sponsor landscape (Third-generation antipsychotic (D2 partial agonist) class)
- Generic (originally Otsuka/BMS) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Abilify — Competitive Intelligence Brief. https://druglandscape.com/ci/aripiprazole. Accessed 2026-05-13.
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