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Ara-C, Mitoxantrone, Daunorubicin, Thioguanin — Competitive Intelligence Brief
phase 3
Combination chemotherapy regimen
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ara-C, Mitoxantrone, Daunorubicin, Thioguanin (Ara-C, Mitoxantrone, Daunorubicin, Thioguanin) — Prof. Dr. Wolfgang Hiddemann. This is a combination chemotherapy regimen that includes cytarabine (Ara-C), mitoxantrone, daunorubicin, and thioguanine, which work together to inhibit DNA synthesis and induce apoptosis in leukemic cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ara-C, Mitoxantrone, Daunorubicin, Thioguanin TARGET | Ara-C, Mitoxantrone, Daunorubicin, Thioguanin | Prof. Dr. Wolfgang Hiddemann | phase 3 | Combination chemotherapy regimen | ||
| Dexamethasona, Idarubicine, ARA-C, Methotrexate | Dexamethasona, Idarubicine, ARA-C, Methotrexate | PETHEMA Foundation | marketed | Combination chemotherapy regimen | ||
| chemotherapy of mFOLFOX6 or FOLFIRI | chemotherapy of mFOLFOX6 or FOLFIRI | Xu jianmin | marketed | Combination chemotherapy regimen | Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin) | |
| CVP | CVP | SCRI Development Innovations, LLC | marketed | Combination chemotherapy regimen | ||
| Consolidation Chemotherapy | Consolidation Chemotherapy | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | marketed | Combination chemotherapy regimen | ||
| FEC | FEC | Hoffmann-La Roche | marketed | Combination chemotherapy regimen | ||
| PTH followed by dose dense AC of FEC | PTH followed by dose dense AC of FEC | Agendia | marketed | Combination chemotherapy regimen with monoclonal antibody | HER2 receptor; microtubule; DNA (topoisomerase II) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination chemotherapy regimen class)
- Sun Yat-sen University · 5 drugs in this class
- Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- University Hospital, Bordeaux · 2 drugs in this class
- Beijing Friendship Hospital · 1 drug in this class
- Centre Hospitalier Universitaire Dijon · 1 drug in this class
- Amgen · 1 drug in this class
- Chungnam National University Hospital · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Children's Cancer Group, China · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ara-C, Mitoxantrone, Daunorubicin, Thioguanin — Competitive Intelligence Brief. https://druglandscape.com/ci/ara-c-mitoxantrone-daunorubicin-thioguanin. Accessed 2026-05-17.
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