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APVAC1 vaccine plus Poly-ICLC and GM-CSF — Competitive Intelligence Brief

APVAC1 vaccine plus Poly-ICLC and GM-CSF (APVAC1 vaccine plus Poly-ICLC and GM-CSF) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Personalized neoantigen vaccine. Area: Oncology.

phase 1 Personalized neoantigen vaccine Tumor antigens Oncology Small molecule Live · refreshed every 30 min

Target snapshot

APVAC1 vaccine plus Poly-ICLC and GM-CSF (APVAC1 vaccine plus Poly-ICLC and GM-CSF) — Immatics Biotechnologies GmbH. APVAC1 vaccine targets tumor antigens, Poly-ICLC is a Toll-like receptor 3 agonist, and GM-CSF is a granulocyte-macrophage colony-stimulating factor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
APVAC1 vaccine plus Poly-ICLC and GM-CSF TARGET APVAC1 vaccine plus Poly-ICLC and GM-CSF Immatics Biotechnologies GmbH phase 1 Personalized neoantigen vaccine Tumor antigens
aMIL aMIL Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins marketed Personalized neoantigen vaccine Patient-specific tumor neoantigens
SK-PC-B70M SK-PC-B70M SK Chemicals Co., Ltd. phase 3 Cancer vaccine (personalized neoantigen vaccine)
IMA901 IMA901 Immatics Biotechnologies GmbH phase 3 Personalized neoantigen vaccine Patient-specific tumor neoantigens
IO102-IO103 IO102-IO103 IO Biotech phase 3 Personalized neoantigen vaccine + checkpoint inhibitor combination Patient-specific neoantigens; CTLA-4
mRNA-1010 mRNA-1010 ModernaTX, Inc. phase 3 Personalized neoantigen vaccine Patient-specific tumor neoantigens
PACMx5 PACMx5 SWOG Cancer Research Network phase 3 Personalized neoantigen vaccine

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Personalized neoantigen vaccine class)

  1. Immatics Biotechnologies GmbH · 2 drugs in this class
  2. ModernaTX, Inc. · 1 drug in this class
  3. SWOG Cancer Research Network · 1 drug in this class
  4. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · 1 drug in this class

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Cite this brief

Drug Landscape (2026). APVAC1 vaccine plus Poly-ICLC and GM-CSF — Competitive Intelligence Brief. https://druglandscape.com/ci/apvac1-vaccine-plus-poly-iclc-and-gm-csf. Accessed 2026-05-17.

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