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APVAC1 vaccine plus Poly-ICLC and GM-CSF — Competitive Intelligence Brief
phase 1
Personalized neoantigen vaccine
Tumor antigens
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
APVAC1 vaccine plus Poly-ICLC and GM-CSF (APVAC1 vaccine plus Poly-ICLC and GM-CSF) — Immatics Biotechnologies GmbH. APVAC1 vaccine targets tumor antigens, Poly-ICLC is a Toll-like receptor 3 agonist, and GM-CSF is a granulocyte-macrophage colony-stimulating factor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| APVAC1 vaccine plus Poly-ICLC and GM-CSF TARGET | APVAC1 vaccine plus Poly-ICLC and GM-CSF | Immatics Biotechnologies GmbH | phase 1 | Personalized neoantigen vaccine | Tumor antigens | |
| aMIL | aMIL | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | marketed | Personalized neoantigen vaccine | Patient-specific tumor neoantigens | |
| SK-PC-B70M | SK-PC-B70M | SK Chemicals Co., Ltd. | phase 3 | Cancer vaccine (personalized neoantigen vaccine) | ||
| IMA901 | IMA901 | Immatics Biotechnologies GmbH | phase 3 | Personalized neoantigen vaccine | Patient-specific tumor neoantigens | |
| IO102-IO103 | IO102-IO103 | IO Biotech | phase 3 | Personalized neoantigen vaccine + checkpoint inhibitor combination | Patient-specific neoantigens; CTLA-4 | |
| mRNA-1010 | mRNA-1010 | ModernaTX, Inc. | phase 3 | Personalized neoantigen vaccine | Patient-specific tumor neoantigens | |
| PACMx5 | PACMx5 | SWOG Cancer Research Network | phase 3 | Personalized neoantigen vaccine |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Personalized neoantigen vaccine class)
- Immatics Biotechnologies GmbH · 2 drugs in this class
- ModernaTX, Inc. · 1 drug in this class
- SWOG Cancer Research Network · 1 drug in this class
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · 1 drug in this class
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Cite this brief
Drug Landscape (2026). APVAC1 vaccine plus Poly-ICLC and GM-CSF — Competitive Intelligence Brief. https://druglandscape.com/ci/apvac1-vaccine-plus-poly-iclc-and-gm-csf. Accessed 2026-05-17.
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