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Aprepitant+Tropisetron — Competitive Intelligence Brief
phase 3
NK1 receptor antagonist + 5-HT3 receptor antagonist combination
NK1 receptor (aprepitant); 5-HT3 receptor (tropisetron)
Oncology / Supportive Care
Small molecule
Live · refreshed every 30 min
Target snapshot
Aprepitant+Tropisetron (Aprepitant+Tropisetron) — Sun Yat-sen University. Aprepitant blocks neurokinin-1 (NK1) receptors while tropisetron blocks 5-HT3 receptors, together preventing chemotherapy-induced nausea and vomiting through dual antiemetic pathways.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Aprepitant+Tropisetron TARGET | Aprepitant+Tropisetron | Sun Yat-sen University | phase 3 | NK1 receptor antagonist + 5-HT3 receptor antagonist combination | NK1 receptor (aprepitant); 5-HT3 receptor (tropisetron) | |
| Aprepitant plus Ondansetron | Aprepitant plus Ondansetron | University of Pittsburgh | marketed | NK1 receptor antagonist + 5-HT3 receptor antagonist combination | NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NK1 receptor antagonist + 5-HT3 receptor antagonist combination class)
- Sun Yat-sen University · 1 drug in this class
- University of Pittsburgh · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Aprepitant+Tropisetron — Competitive Intelligence Brief. https://druglandscape.com/ci/aprepitant-tropisetron. Accessed 2026-06-10.
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