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Aprepitant+Tropisetron — Competitive Intelligence Brief

Aprepitant+Tropisetron (Aprepitant+Tropisetron) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NK1 receptor antagonist + 5-HT3 receptor antagonist combination. Area: Oncology / Supportive Care.

phase 3 NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (tropisetron) Oncology / Supportive Care Small molecule Live · refreshed every 30 min

Target snapshot

Aprepitant+Tropisetron (Aprepitant+Tropisetron) — Sun Yat-sen University. Aprepitant blocks neurokinin-1 (NK1) receptors while tropisetron blocks 5-HT3 receptors, together preventing chemotherapy-induced nausea and vomiting through dual antiemetic pathways.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Aprepitant+Tropisetron TARGET Aprepitant+Tropisetron Sun Yat-sen University phase 3 NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (tropisetron)
Aprepitant plus Ondansetron Aprepitant plus Ondansetron University of Pittsburgh marketed NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NK1 receptor antagonist + 5-HT3 receptor antagonist combination class)

  1. Sun Yat-sen University · 1 drug in this class
  2. University of Pittsburgh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Aprepitant+Tropisetron — Competitive Intelligence Brief. https://druglandscape.com/ci/aprepitant-tropisetron. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing