Who are APOKYN's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Aripiprazole Augmentation, Pramipexole (Mirapex), Quetiapine and Topiramate, Adjunctive asenapine, LYBALVI, Placebo Asenapine.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

APOKYN — Competitive Intelligence Brief

APOKYN (APOKYN) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dopaminergic Agonist. Area: Neuroscience.

marketed Dopaminergic Agonist D(2) dopamine receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

APOKYN (APOKYN) — MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
APOKYN TARGET	APOKYN	MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals	marketed	Dopaminergic Agonist	D(2) dopamine receptor
Aripiprazole Augmentation	Aripiprazole Augmentation	Centre for Addiction and Mental Health	marketed	Atypical antipsychotic / dopamine partial agonist	D2 dopamine receptor, 5-HT1A serotonin receptor
Pramipexole (Mirapex)	Pramipexole (Mirapex)	Massachusetts General Hospital	marketed	Dopamine agonist	D2 dopamine receptor, D3 dopamine receptor
Quetiapine and Topiramate	Quetiapine and Topiramate	University of Cincinnati	marketed	Atypical antipsychotic + anticonvulsant mood stabilizer combination	D2 dopamine receptor, 5-HT2A serotonin receptor (quetiapine); voltage-gated sodium channels, carbonic anhydrase (topiramate)
Adjunctive asenapine	Adjunctive asenapine	Lori Davis, MD	marketed	Atypical antipsychotic	D2 dopamine receptor, 5-HT2A serotonin receptor
LYBALVI	LYBALVI	Alkermes, Inc.	marketed	Atypical antipsychotic with opioid antagonist	D2 dopamine receptor, 5-HT7 serotonin receptor, mu-opioid receptor
Placebo Asenapine	Placebo Asenapine	Organon and Co	phase 3	Atypical antipsychotic	D2 dopamine receptor, 5-HT2A serotonin receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dopaminergic Agonist class)

MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals · 1 drug in this class
Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). APOKYN — Competitive Intelligence Brief. https://druglandscape.com/ci/apokyn. Accessed 2026-05-15.

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