Who are APG-115's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Venetoclax; Rituximab, Venclexta, Ixempra Kit, Rd, Perazyl, Venetoclax (VEN).

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

APG-115 — Competitive Intelligence Brief

APG-115 (APG-115) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: BCL-2 inhibitor. Area: Oncology.

phase 2 BCL-2 inhibitor BCL-2 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

APG-115 (APG-115) — Ascentage Pharma Group Inc.. APG-115 is a small molecule inhibitor of BCL-2 family proteins.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
APG-115 TARGET	APG-115	Ascentage Pharma Group Inc.	phase 2	BCL-2 inhibitor	BCL-2
Venetoclax; Rituximab	venetoclax-rituximab	Pfizer	marketed	BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab)	BCL-2 (venetoclax); CD20 (rituximab)	N/A
Venclexta	venetoclax	AbbVie	marketed	BCL-2 Inhibitor [EPC]	Apoptosis regulator Bcl-2	2014-01-01
Ixempra Kit	IXABEPILONE	R-Pharm Us Llc	marketed	Microtubule Inhibitor	Apoptosis regulator Bcl-2	2007-01-01
Rd	Rd	Ascentage Pharma Group Inc.	marketed	BCL-2 inhibitor	BCL-2
Perazyl	CHLORCYCLIZINE		marketed	chlorcyclizine	Apoptosis regulator Bcl-2
Venetoclax (VEN)	Venetoclax (VEN)	Nanfang Hospital, Southern Medical University	marketed	BCL-2 inhibitor	BCL-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2030-05-26 — Venclexta · 9174982 · US
2031-06-27 — Venclexta · 8546399 · US
2031-11-21 — Venclexta · 10730873 · US
2032-01-29 — Venclexta · 8722657 · US
2032-05-23 — Venclexta · 11369599 · US
2033-09-06 — Venclexta · 11110087 · US
2033-09-06 — Venclexta · 11590128 · US
2033-09-06 — Venclexta · 10993942 · US
2033-09-06 — Venclexta · 9539251 · US
2033-09-06 — Venclexta · 11413282 · US

Sponsor landscape (BCL-2 inhibitor class)

Ascentage Pharma Group Inc. · 2 drugs in this class
Grupo Argentino de Tratamiento de la Leucemia Aguda · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
NHS Greater Glasgow and Clyde · 1 drug in this class
Nanfang Hospital, Southern Medical University · 1 drug in this class
PrECOG, LLC. · 1 drug in this class
Stichting Hemato-Oncologie voor Volwassenen Nederland · 1 drug in this class
The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). APG-115 — Competitive Intelligence Brief. https://druglandscape.com/ci/apg-115. Accessed 2026-05-13.

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