Last reviewed · How we verify
Anti-VEGF treatment — Competitive Intelligence Brief
phase 2
Anti-angiogenic agent
VEGF
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Anti-VEGF treatment (Anti-VEGF treatment) — Vastra Gotaland Region. Anti-VEGF treatment works by inhibiting the vascular endothelial growth factor (VEGF) pathway, which is involved in angiogenesis and tumor growth.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Anti-VEGF treatment TARGET | Anti-VEGF treatment | Vastra Gotaland Region | phase 2 | Anti-angiogenic agent | VEGF | |
| PONATINIB HYDROCHLORIDE | PONATINIB HYDROCHLORIDE | marketed | ABL, T315I mutant ABL, VEGFR, PDGFR, FGFR, EPH receptors, SRC family, KIT, RET, TIE2, FLT3 | 2012-01-01 | ||
| REGORAFENIB | REGORAFENIB | marketed | RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAF V600E, SAPK2, PTK5, Abl, CSF1R | 2012-01-01 | ||
| Inlyta | Axitinib | Pfizer | marketed | Receptor tyrosine kinase inhibitor | Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3 | 2012-01-01 |
| PAZOPANIB HYDROCHLORIDE | PAZOPANIB HYDROCHLORIDE | marketed | VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms | 2009-01-01 | ||
| PAZOPANIB | PAZOPANIB | marketed | Kinase Inhibitor [EPC] | VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-ɑ, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms | 2009-01-01 | |
| Sutent | Sunitinib Malate | Pfizer | marketed | Small molecule kinase inhibitor | Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET | 2006-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anti-angiogenic agent class)
- Bayer · 1 drug in this class
- Vastra Gotaland Region · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Anti-VEGF treatment — Competitive Intelligence Brief. https://druglandscape.com/ci/anti-vegf-treatment. Accessed 2026-05-16.
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